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Integrated Use of Virtual Bronchoscopy and Endobronchial Ultrasonography on the Diagnosis of Peripheral Lung Lesions

机译:虚拟支气管镜和支气管内超声的综合应用在周围型肺病变的诊断中

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Summary: Endobronchial ultrasound (EBUS) improves bronchoscopic diagnosis of peripheral lung lesions (PLLs). The procedure time is lengthened by the search through multiple bronchial branches to PLLs. Virtual bronchoscopy (VB) provides endobronchial views that simulate findings at bronchoscopy. An open source software can be employed to study VB and hence the endobronchial route to a PLL. It allows VB to be studied in a Macintosh platform such as a laptop computer. Our purpose was to test if VB generated by this software could shorten procedure time of EBUS-guided bronchoscopy as compared with no VB assistance. The most feasible route to a PLL was manually selected using this software to study VB (VB group). For non-VB group, 2D CT axial + /- coronal images were reviewed to plan bronchoscopy. Before bronchoscopic biopsies, the location of PLL was confirmed by EBUS. Thirty-three subjects were recruited including 16 in VB group and 17 in non-VB group. The mean EBUS examination time and mean total procedure time were reduced in the VB group compared with non-VB group: 5.3 versus 10.5 minutes (P = 0.04) and 22.4 versus 29.9 minutes (P = 0.044), respectively. There was no complication in the VB group. Although the diagnostic yield was higher in the VB group than non-VB group, our study was not powered to test the difference. This pilot study suggests that VB assistance is safe and shortens procedural time of EBUS-guided bronchoscopy for PLL. Further study is warranted to confirm these findings.
机译:摘要:支气管内超声(EBUS)改善了支气管镜对周围肺部病变(PLL)的诊断。通过对PLL的多个支气管分支进行搜索,可以延长过程时间。虚拟支气管镜检查(VB)提供了可模拟支气管镜检查结果的支气管内视图。可以使用开源软件来研究VB,从而研究通向PLL的支气管内途径。它允许在Macintosh平台(例如膝上型计算机)中研究VB。我们的目的是测试与没有VB协助的情况相比,此软件生成的VB是否可以缩短EBUS引导的支气管镜检查的过程时间。使用该软件手动选择最可行的PLL路径来研究VB(VB组)。对于非VB组,检查2D CT轴向+/-冠状动脉图像以计划支气管镜检查。在支气管镜活检之前,通过EBUS确认了PLL的位置。招募了33位受试者,其中VB组16位,非VB组17位。与非VB组相比,VB组的平均EBUS检查时间和平均总手术时间减少了:分别为5.3分钟和10.5分钟(P = 0.04)和22.4分钟和29.9分钟(P = 0.044)。 VB组没有并发症。尽管VB组的诊断率高于非VB组,但我们的研究无力检验差异。这项初步研究表明,VB辅助是安全的,并且可以缩短EBUS引导的用于PLL的支气管镜检查的时间。有必要进一步研究以确认这些发现。

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