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首页> 外文期刊>Journal of bronchology & interventional pulmonology >Survey of Academic Pulmonologists, Oncologists, and Infectious Disease Physicians on the Rote of Bronchoscopy in Managing Hematopoietic Stem Cell Transplantation Patients With Pulmonary Infiltrates
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Survey of Academic Pulmonologists, Oncologists, and Infectious Disease Physicians on the Rote of Bronchoscopy in Managing Hematopoietic Stem Cell Transplantation Patients With Pulmonary Infiltrates

机译：在处理肺部浸润的造血干细胞移植患者中，支气管镜旋转的学术肺病学家，肿瘤学家和传染病医师的调查

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Background: In the absence of evidence-based guidelines, there is potential for variability in the management of hematopoietic stem cell transplantation (HSCT) patients with pulmonary infiltrates. We decided to perform a nationwide survey of pulmonologists, oncologists, and infectious disease physicians on the role of bronchoscopy in managing HSCT patients.Methods: An 18-question survey was prepared, and after being internally reviewed it was sent through electronic mail to all hematology oncology, pulmonary and critical care, and infectious disease fellowship programs in the United States. Both faculty and fellows from all training programs were asked to electronically fiE out the survey.Results: A total of 167 responses, representing 76 different institutions were collected (62 pulmonary, 49 oncology, 53 infectious disease). Pulmonologists felt that bronchoscopy was less likely to yield a positive result or change pharmacological therapy (P-value = 0.02 and 0.02). With regard to timing for bronchoscopy in HSCT recipients, there was consensus between all the 3 groups that patients who are non-neutropenic and do not have cavitating infiltrates on chest computed tomography scan should receive bronchoscopy only after failure of empiric antimicrobial therapy. However, there was no agreement between the 3 groups on when neutropenic patients or those with cavitating lesions should receive bronchoscopy.Conclusions: In the absence of randomized clinical trials and evidence-based guidelines, disparities exist in the use of bronchoscopy in the management of infiltrates. These differences were observed within and between both specialties. This study reflects the need for further research to better define the role of bronchoscopy in these patients.
机译：背景：在缺乏循证指南的情况下，肺部浸润的造血干细胞移植（HSCT）患者的治疗存在差异性。我们决定在全国范围内对肺科医师，肿瘤学家和传染病医师进行调查，探讨支气管镜检查在管理HSCT患者中的作用。方法：准备了18个问题的调查表，并在内部审查后通过电子邮件发送给所有血液学美国的肿瘤学，肺部和重症监护以及传染病研究金计划。结果：总共收集了代表76个不同机构的167个响应（代表62个肺部，49个肿瘤科，53个传染病）。肺科医生认为，支气管镜检查不太可能产生阳性结果或改变药理疗法（P值分别为0.02和0.02）。关于HSCT接受者进行支气管镜检查的时间，三组之间的共识是，非中性粒细胞减少和在胸部CT检查中没有空化浸润的患者仅应在经验性抗微生物治疗失败后才接受支气管镜检查。然而，三组之间在中性粒细胞减少症患者或患有空洞性病变的患者何时应接受支气管镜检查方面并没有达成共识。结论：在缺乏随机临床试验和循证指南的情况下，在治疗渗透物中使用支气管镜检查存在差异。这些差异在两个专业之内和之间都可以观察到。这项研究反映了需要进一步研究以更好地定义支气管镜在这些患者中的作用。

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