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首页> 外文期刊>Clinical journal of sport medicine: official journal of the Canadian Academy of Sport Medicine >Articular cartilage repair in the adolescent athlete: is autologous chondrocyte implantation the answer?
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Articular cartilage repair in the adolescent athlete: is autologous chondrocyte implantation the answer?

机译：青少年运动员的关节软骨修复：自体软骨细胞植入是答案吗？

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OBJECTIVE: To determine the evidence base for recommendations regarding autologous chondryocyte implantation in adolescent athletes. MATERIALS AND METHODS: All literature on articular cartilage repair from MEDLINE search dated 1990 to 2006 was reviewed. The majority of articles describe surgical technique and indications. Three techniques for secondary articular cartilage repair have been identified: autologous chondrocyte implantation, autologous osteochondral implants, and marrow stimulation techniques. The initial literature search identified 4 studies that reported the effectiveness and durability of autologous chondrocyte implantation in adults and 2 studies that reported the outcomes of autologous chondrocyte implantation in adolescent athletes. No results of osteochondral implantation or marrow stimulation techniques in adolescent athletes have been published. RESULTS: Acceptable repair rates with all 3 techniques have been reported in adult athletes. Two studies reported high success using autolgous chondrocyte implantation (ACI) in children. CONCLUSIONS: Articular cartilage injury in young athletes remains a difficult problem. The ideal situation is early diagnosis and primary repair, particularly with lesions of the knee, elbow, and ankle. In cases where primary repair is not possible or has been unsuccessful and the lesion is large or symptomatic, secondary repair with either marrow stimulation, microfracture, autologous chondrocyte implantation, or autologous osteochondral grafting may be used. However, at present only the results of ACI repair have been reported for adolescent athletes.
机译：目的：为青少年运动员自体软骨细胞植入的建议确定证据基础。材料与方法：回顾了1990年至2006年MEDLINE搜索的所有有关关节软骨修复的文献。大多数文章介绍了手术技术和适应症。已经确定了三种用于二次关节软骨修复的技术：自体软骨细胞植入，自体骨软骨植入物和骨髓刺激技术。最初的文献检索发现了4篇报道了成人自体软骨细胞植入的有效性和持久性的研究，以及2篇报道了自体软骨细胞植入青少年运动员的结果的研究。尚未发表青少年运动员的骨软骨植入或骨髓刺激技术的结果。结果：成人运动员使用这三种技术的修复率均可接受。两项研究报告了在儿童中使用自体软骨细胞植入（ACI）取得的巨大成功。结论：年轻运动员的关节软骨损伤仍然是一个难题。理想的情况是早期诊断和初步修复，尤其是膝盖，肘部和脚踝的病变。如果无法进行一级修复或修复不成功且病变较大或有症状，则可以采用骨髓刺激，微骨折，自体软骨细胞植入或自体骨软骨移植进行二次修复。但是，目前仅报道了青少年运动员ACI修复的结果。

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