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首页> 外文期刊>Journal of cardiology >Association between obstructive sleep apnea and premature supraventricular contractions
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Association between obstructive sleep apnea and premature supraventricular contractions

机译：阻塞性睡眠呼吸暂停与室上性早搏之间的关联

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Objective: The exact association between obstructive sleep apnea (OSA) and premature supraventricular contractions (PSVCs) has not been established. Methods: We prospectively performed polysomnography together with 24-hour Holter electrocardiography in 431 patients who were clinically suspected of having OSA and examined the association between OSA severity and PSVCs during wakefulness and sleep. The patients were classified into 4 groups according to the apnea-hypopnea index (AHI) quartiles (Q1 = patients with AHI < 13.8, Q2 = those with 13.8 ≤ AHI < 28.8, Q3 = those with 28.8 ≤ AHI < 48.1, Q4 = those with AHI ≥ 48.1). Results: The number of PSVCs/hour during sleep differed significantly among the 4 groups, but the number of PSVCs/hour during wakefulness did not. The prevalence of PSVC ≥ 5/hour during sleep was significantly higher in Q4 (21.0%) than the other 3 groups (Q1, 9.0%; Q2, 8.0%; Q3, 6.0%; all p< 0.05 for Q4), but the prevalence of PSVC ≥ 5/hour during wakefulness did not differ among the 4 groups. A multivariate logistic regression analysis showed that the highest AHI quartile was significantly associated with PSVC ≥ 5/hour during sleep (odds ratio 3.04, 95% confidence interval 1.44-6.42, p= 0.004). Conclusions: Severe OSA can cause PSVCs during sleep, but its effect appears not to be strong. Further studies are needed to clarify the clinical significance of this small but significant increase in PSVCs during sleep in severe OSA patients.
机译：目的：尚无阻塞性睡眠呼吸暂停（OSA）与室上性早搏（PSVC）之间的确切关联。方法：我们对431名临床怀疑患有OSA的患者进行了多导睡眠监测和24小时动态心电图检查，并检查了清醒和睡眠期间OSA严重程度与PSVC之间的关系。根据呼吸暂停低通气指数（AHI）四分位数将患者分为4组（Q1 = AHI <13.8的患者，Q2 = 13.8≤AHI <28.8的患者，Q3 = 28.8≤AHI <48.1的患者，Q4 =那些AHI≥48.1）。结果：睡眠期间的PSVCs /小时数在4组之间有显着差异，但觉醒期间的PSVCs /小时数没有差异。第4季度睡眠期间PSVC≥5 /小时的患病率（21.0％）明显高于其他3组（Q1，9.0％; Q2，8.0％; Q3，6.0％; Q4的所有p <0.05），但觉醒期间PSVC≥5 /小时的患病率在4组之间没有差异。多元logistic回归分析显示，最高AHI四分位数与睡眠期间PSVC≥5 /小时显着相关（优势比3.04，95％置信区间1.44-6.42，p = 0.004）。结论：严重的OSA可以在睡眠期间引起PSVC，但其作用似乎并不强。需要进一步的研究来阐明重度OSA患者睡眠期间PSVC的这种微小但显着增加的临床意义。

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