...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of cardiopulmonary rehabilitation >The relationship between C-reactive protein and other cardiovascular risk factors in men and women.
【24h】

The relationship between C-reactive protein and other cardiovascular risk factors in men and women.

机译：男性中C反应蛋白与其他心血管危险因素的关系。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

INTRODUCTION: C-reactive protein (CRP) has emerged as an important indicator of risk for cardiovascular disease. The impact of gender on the relationship between CRP and other cardiovascular risk factors, however, has not been thoroughly investigated. METHODS: Ninety men and 75 women participated in this study. Age, resting systolic and diastolic blood pressure, resting heart rate, body mass index, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, and hs-CRP were ascertained. Maximal oxygen consumption was obtained via treadmill testing, and aortic stiffness was measured using magnetic resonance imaging. RESULTS: Log hs-CRP level was significantly higher in the female subjects compared with the males subjects (0.86 +/- 0.67 mg/L vs 0.63 +/- 0.44 mg/L, respectively; P = .003). In the male group, Pearson product moment correlation analysis showed that log hs-CRP was not significantly correlated (P > .10) with any of the other variables of interest. In the female group, however, log hs-CRP was significantly correlated (P < .05) with total cholesterol (r = 0.30), low-density lipoprotein (r = 0.27), tryglycerides (r = 0.51), and body mass index (r = 0.36). Linear regression analysis determined that triglycerides and body mass index explained 30% of the variability in log hs-CRP. CONCLUSIONS: These results indicate that the relationship between CRP and other cardiac risk factors is different between apparently healthy men and women. The prognostic characteristics of CRP and the impact of statin therapy on CRP may therefore differ between men and women. Future research should be directed toward resolving this issue.
机译：简介：C反应蛋白（CRP）已成为心血管疾病风险的重要指标。性别对CRP和其他心血管危险因素之间关系的影响尚未得到彻底调查。方法：90名男性和75名女性参加了这项研究。确定年龄，静息收缩压和舒张压，静息心率，体重指数，总胆固醇，高密度脂蛋白，低密度脂蛋白，甘油三酸酯和hs-CRP。通过跑步机测试获得最大的氧气消耗，并使用磁共振成像测量主动脉僵硬度。结果：与男性受试者相比，女性受试者的log hs-CRP水平显着更高（分别为0.86 +/- 0.67 mg / L和0.63 +/- 0.44 mg / L; P = 0.003）。在男性组中，Pearson乘积矩相关分析表明，log hs-CRP与其他任何相关变量均无显着相关性（P> .10）。然而，在女性组中，log hs-CRP与总胆固醇（r = 0.30），低密度脂蛋白（r = 0.27），甘油三酸酯（r = 0.51）和体重指数显着相关（P <.05） （r ＝ 0.36）。线性回归分析确定甘油三酸酯和体重指数解释了log hs-CRP变异的30％。结论：这些结果表明，在明显健康的男性和女性之间，CRP和其他心脏危险因素之间的关系是不同的。因此，CRP的预后特征以及他汀类药物疗法对CRP的影响在男女之间可能有所不同。未来的研究应该针对解决这个问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号