首页> 外文期刊>Journal of Cancer Research and Clinical Oncology >Follicular variant of papillary thyroid carcinoma (FVPTC): histological features, BRAF V600E mutation, and lymph node status
【24h】

Follicular variant of papillary thyroid carcinoma (FVPTC): histological features, BRAF V600E mutation, and lymph node status

机译:甲状腺乳头状癌滤泡变体(FVPTC):组织学特征,BRAF V600E突变和淋巴结状态

获取原文
获取原文并翻译 | 示例
           

摘要

Follicular variant of papillary thyroid carcinoma (FVPTC) is currently treated like conventional papillary thyroid carcinoma (cPTC). Recent reports indicate that encapsulated FVPTC behaves like follicular adenomas, while infiltrative FVPTC behaves like cPTC. This raises the possibility that histology and/or mutation status might help personalize management of FVPTC regarding extent of surgery, intensity of follow-up, and targeted therapy. This study correlates histological features, immunoreactivity for CK19, HBME, and Gal, and BRAF V600E mutation with lymph node (LN) metastasis and follow-up in FVPTC.
机译:乳头状甲状腺癌(FVPTC)的滤泡变体目前像常规甲状腺乳头状癌(cPTC)一样进行治疗。最近的报道表明封装的FVPTC的行为类似于滤泡性腺瘤,而浸润性FVPTC的行为类似于cPTC。这增加了组织学和/或突变状态可能有助于对FVPTC进行个性化管理的可能性,涉及手术程度,随访强度和靶向治疗。这项研究将CK19,HBME和Gal的组织学特征,免疫反应性以及BRAF V600E突变与FVPTC的淋巴结转移和随访相关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号