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首页> 外文期刊>Journal of child psychology and psychiatry >Cognitive impairments are different in single-incidence and multi-incidence ADHD families
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Cognitive impairments are different in single-incidence and multi-incidence ADHD families

机译:单发和多发ADHD家庭的认知障碍有所不同

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BackgroundWe may improve our understanding of the role of common versus unique risk factors in attention-deficit/hyperactivity disorder (ADHD) by examining ADHD-related cognitive deficits in single- (SPX), and multi-incidence (MPX) families. Given that individuals from multiplex (MPX) families are likely to share genetic vulnerability for the disorder, whereas simplex (SPX) ADHD may be the result of sporadic (non-)genetic causes unique to the patient, we hypothesized that cognitive impairments may be different in SPX and MPX ADHD as indicated by (a) the presence of cognitive deficits in MPX, but not SPX unaffected siblings and (b) dissimilar cognitive profiles in SPX and MPX ADHD patients.
机译:背景我们可能会通过检查单发(SPX)和多发性(MPX)家庭中与ADHD相关的认知缺陷来增进对常见危险因素和独特危险因素在注意力缺陷/多动障碍(ADHD)中作用的理解。鉴于来自多重(MPX)家族的个体可能共享该疾病的遗传易感性,而单纯形(SPX)ADHD可能是患者独特的偶发性(非遗传性)原因的结果,我们假设认知障碍可能有所不同在SPX和MPX ADHD患者中表现为(a)在MPX中存在认知缺陷,但在SPX中未受影响的兄弟姐妹中不存在;以及(b)在SPX和MPX ADHD患者中认知特征不同。

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