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首页> 外文期刊>Journal of Chemical Technology & Biotechnology >Recent advances in production and biotechnological applications of thermostable and alkaline bacterial lipases
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Recent advances in production and biotechnological applications of thermostable and alkaline bacterial lipases

机译:热稳定和碱性细菌脂肪酶在生产和生物技术应用方面的最新进展

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摘要

Microbial lipases occupy a vital position with respect to their industrial applications and they are studied extensively. Thermophilic microorganisms are potential sources of thermostable alkaline lipases, which have been isolated from various natural origins. Most lipases can act in a wide range of pH and temperature, though alkaline bacterial lipases are more common. Thermostable alkaline lipases have commercial value and find applications in various industrial and biotechnological sectors such as additives in detergents, additives in food industries, environmental bioremediations and in molecular biology. The latest trend in lipase research is the development of novel and improved lipases through molecular approaches such as directed evolution and exploring natural communities by the metagenomic approach. Therefore, thermostable alkaline lipases are the enzymes of choice for many biotechnologists, microbiologists, biochemists, environmentalists and biochemical engineers. In the present review, we discuss some novel sources along with recent advances in fermentation conditions, substrate conditions and biotechnological applications of thermostable alkaline bacterial lipases.
机译:微生物脂肪酶在其工业应用中占据着至关重要的位置,并且已被广泛研究。嗜热微生物是热稳定碱性脂肪酶的潜在来源,其已从各种天然来源中分离出来。尽管碱性细菌脂肪酶更为常见,但大多数脂肪酶都可以在很宽的pH和温度范围内起作用。耐高温碱性脂肪酶具有商业价值,并在各种工业和生物技术领域得到应用,例如洗涤剂中的添加剂,食品工业中的添加剂,环境生物修复和分子生物学中的添加剂。脂肪酶研究的最新趋势是通过分子方法(例如定向进化和通过宏基因组学方法探索自然群落)开发新型和改良的脂肪酶。因此,热稳定的碱性脂肪酶是许多生物技术人员,微生物学家,生物化学家,环保主义者和生物化学工程师的首选酶。在当前的审查中,我们讨论了一些新的来源,以及热稳定碱性细菌脂肪酶在发酵条件,底物条件和生物技术应用方面的最新进展。

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