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Synthesis of dihydrobenzo[b]pyrimido[4,5-e][1,4]thiazepines; derivatives of a novel ring system

机译:二氢苯并[b]嘧啶[4,5-e] [1,4]噻氮平的合成;新型环系统的导数

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摘要

Several derivatives of the novel dihydrobenzo[b]pyrimido[4,5-e][1,4]thiazepine ring system have been synthesised through the initial heterocyclisation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine with o-aminothiophenol followed by treatment with various secondary amines in boiling ethanol.
机译:通过2,4-二氯-5-(氯甲基)-6-甲基嘧啶与杂环的初始杂环化,已经合成了新型二氢苯并[b]嘧啶基[4,5-e] [1,4]硫氮杂ze环系统的几种衍生物-氨基苯硫酚,然后在沸腾的乙醇中用各种仲胺处理。

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