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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Clinical efficacy of prostate cancer detection using power doppler imaging in American and Japanese men.
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Clinical efficacy of prostate cancer detection using power doppler imaging in American and Japanese men.

机译：使用功率多普勒成像技术在美国和日本男性中检测前列腺癌的临床疗效。

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PurposeThe aim of this study was to compare the detection rates of tumor vascular flow as measured by power Doppler imaging (PDI) in 2 populations and to determine whether PDI can reduce the number of unnecessary prostate biopsies in men with serum prostate-specific antigen (PSA) concentrations less than 10.1 ng/ml.MethodsThe patient populations were Japanese (group 1) and American (group 2) men with either serum PSA concentrations of 4.1-10.0 ng/ml or abnormal findings on digital rectal examination (DRE) plus PSA concentrations less than 4.1 ng/ml. We compared the overall diagnostic accuracy of DRE, gray-scale transrectal sonography (TRUS), and PDI between the 2 groups.ResultsIn total, 275 men were studied, 154 in group 1 and 121 in group 2. Cancer was identified in 27% of men in group 1 and in 60% of group 2. Men with cancer in both groups differed significantly in age, peripheral zone volume, and mean number of positive biopsy cores. The sensitivity and specificity of PDI in group 2 were significantly inferior to those in group 1. The negative predictive value (NPV) of PDI was significantly higher for group 1 than for group 2. The NPV of PDI in group 1 was equivalent to that for the combination of DRE and TRUS, whereas the NPV for PDI in group 2 was significantly inferior to that of DRE and TRUS.ConclusionsTumor vascularity could be detected by PDI more effectively in Japanese men with cancer than in American men with cancer. We hypothesize that this difference was a result of larger cancer volumes and smaller prostates in the Japanese men. PDI did not provide any performance advantage over DRE and TRUS in avoiding unnecessary biopsies.
机译：目的本研究的目的是比较通过功率多普勒成像（PDI）在2个人群中测得的肿瘤血管流量的检测率，并确定PDI是否可以减少患有血清前列腺特异性抗原（PSA）的男性不必要的前列腺活检的数量）浓度低于10.1 ng / ml。方法患者人群为日本（第1组）和美国（第2组）男性，血清PSA浓度为4.1-10.0 ng / ml或数字直肠检查（DRE）加PSA浓度异常小于4.1 ng / ml。我们比较了两组之间的DRE，灰度直肠超声检查（TRUS）和PDI的总体诊断准确性。结果总共研究了275名男性，其中第一组154例，第二组121例。第1组的男性和第2组的60％的男性两组的男性患者的年龄，外周区容积和活检核心的平均数均存在显着差异。第2组中PDI的敏感性和特异性明显低于第1组。PDI的阴性预测值（NPV）在第1组中明显高于第2组。第1组中PDI的NPV与在第1组中的PNP相当。结论：DRE和TRUS联合使用，而第2组PDI的NPV显着低于DRE和TRUS。结论结论PDI可以更有效地检测日本癌症男性的肿瘤血管。我们假设这种差异是日本男性中癌症体积更大和前列腺较小的结果。在避免不必要的活检方面，PDI没有提供优于DRE和TRUS的任何性能优势。

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