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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Congenital lung malformations in the second trimester: prenatal ultrasound diagnosis and pathologic findings.
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Congenital lung malformations in the second trimester: prenatal ultrasound diagnosis and pathologic findings.

机译：妊娠中期先天性肺畸形：产前超声诊断和病理结果。

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PURPOSE: To correlate prenatal sonographic diagnosis of cystic lung malformations with fetopathologic findings after termination of pregnancy. METHODS: We retrospectively analyzed the data of 16 terminated cases in which a cystic lung lesion was diagnosed pre- or postnatally. RESULTS: On average, prenatal diagnosis was established on the 21(st) gestational week (range, 19-26 weeks). The cause of termination was severe polyhydramnios in 4 cases, nonimmune fetal hydrops in 4 cases, other congenital malformation in 5 cases (renal malformation, 2 cases; congenital diaphragmatic hernia, 3 cases), and obstetrical conditions (intrauterine death, placental abruption, spontaneous abortion) in 3 cases. In 11 cases, congenital cystic adenomatoid malformation (CCAM) was the presumptive prenatal diagnosis. Autopsy confirmed the prenatal diagnosis in 6 of them, while in the other 5 cases, an enteric cyst, a laryngeal atresia, an unidentified tumor, a pulmonary hypoplasia, and an extralobar pulmonary sequestration were found on histologic examination. On the other hand, the autopsy revealed CCAM in those 5 cases in which other malformations were suggested prenatally. CONCLUSION: The prenatal sonographic diagnosis of CCAM is difficult. Our cases emphasize the important role of fetopathology even today in the verification of prenatal diagnosis based on sonographic examinations.
机译：目的：将妊娠终止后胎儿囊性肺畸形的产前超声诊断与胎儿病理学发现相关联。方法：我们回顾性分析了16例在出生前或出生后被诊断出囊性肺病变的终止病例的数据。结果：平均而言，在妊娠第21周（范围19-26周）确定了产前诊断。终止原因为严重羊水过多4例，非免疫性胎儿积水4例，其他先天性畸形5例（肾畸形2例;先天性diaphragm肌疝3例），以及产科情况（宫内死亡，胎盘早剥，自发性）流产）3例。 11例先天性囊性腺瘤样畸形（CCAM）是产前诊断。尸检证实其中有6例是产前诊断，而其他5例在组织学检查中发现有肠囊肿，喉头闭锁，不明肿瘤，肺发育不全和肺叶外肺隔离症。另一方面，尸检显示在这5例产前提示其他畸形的病例中，CCAM被发现。结论：产前超声对CCAM的诊断很困难。我们的病例甚至在今天都强调了胎儿病理学在基于超声检查进行产前诊断验证中的重要作用。

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