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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Value of contrast-enhanced sonography with micro flow imaging in the diagnosis of prostate cancer.
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Value of contrast-enhanced sonography with micro flow imaging in the diagnosis of prostate cancer.

机译：超声造影与微流成像技术在前列腺癌诊断中的价值。

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BACKGROUND: To evaluate the effectiveness of contrast-enhanced sonographic micro flow imaging (MFI) in the diagnosis of prostate cancer. METHODS: A total of 74 patients referred for prostate biopsy were prospectively evaluated with MFI. The abnormalities were categorized into four patterns: pattern 1: indistinct separation between the inner and outer gland; pattern 2: asymmetrical or focally increased enhancement in the outer gland; pattern 3: enhancement with focal defect; pattern 4: enhancement in the outer gland equal to that of the inner gland. The findings were correlated with Gleason scores. RESULTS: Prostate cancer was detected in 264 sites in 41 patients. The sensitivity, specificity, accuracy, and positive and negative predictive values for MFI were 81.1%, 84.3%, 83.3%, 68.6%, and 91.3%, respectively. Positive predictive values for the four patterns were 46.0 (pattern 1), 53.6 (pattern 2), 94.3 (pattern 3), and 95.4 (pattern 4). Gleason scores of cancers with patterns 3 (7.09) or 4 (7.51) were significantly higher than those with patterns 1 (6.17) or 2 (6.59) (p = 0.001, p = 0.005, p < 0.001, p < 0.001). CONCLUSIONS: Some MFI patterns had high positive predictive values and were associated with more aggressive cancers. This could be used to reduce the number of biopsy sites and detect clinically significant cancers.
机译：背景：评价对比增强超声微流成像（MFI）在前列腺癌诊断中的有效性。方法：前瞻性评估了总共74例接受前列腺穿刺活检的患者。异常可分为四种类型：模式1：内外腺分离不清晰;模式2：外腺增强不对称或局部增强;模式3：局部缺陷增强;模式4：外腺的增强等于内腺的增强。这些发现与格里森得分相关。结果：在41名患者的264个部位检测到前列腺癌。 MFI的敏感性，特异性，准确性以及阳性和阴性预测值分别为81.1％，84.3％，83.3％，68.6％和91.3％。这四个模式的阳性预测值为46.0（模式1），53.6（模式2），94.3（模式3）和95.4（模式4）。模式3（7.09）或4（7.51）的癌症的格里森评分显着高于模式1（6.17）或2（6.59）的癌症（p = 0.001，p = 0.005，p <0.001，p <0.001）。结论：某些MFI模式具有较高的阳性预测值，并与更具侵略性的癌症相关。这可用于减少活检部位的数量并检测具有临床意义的癌症。

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