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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Vascular risk in women with a history of severe preeclampsia
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Vascular risk in women with a history of severe preeclampsia

机译：有严重先兆子痫病史的女性的血管风险

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Background. To assess markers of vascular dysfunction and risk in postpartum women with a history of severe preeclampsia. Methods. Carotid intima-media thickness (CIMT) and brachial artery flow-mediated dilatation (FMD) measured by ultrasonography, and lipid profile and insulin resistance evaluated by biochemical assays were compared between 34 women with a history of severe preeclampsia and 42 women with a prior normal pregnancy at least 12-24 months postpartum. Results. CIMT was higher and FMD lower in the preeclamptic than in the control group. We found a significant inverse correlation between CIMT and FMD in the preeclamptic group, but no difference in lipid profiles and insulin resistance between the groups. Conclusions. Women with a history of severe preeclampsia exhibit early structural and functional preatherosclerotic vascular impairment, which might explain their higher risk of future cardiovascular disease.
机译：背景。评估具有严重先兆子痫病史的产后妇女的血管功能障碍和危险标志。方法。通过超声检查测量颈动脉内膜中层厚度（CIMT）和肱动脉血流介导的扩张（FMD），并通过生化分析评估了脂质状况和胰岛素抵抗，对34例患有严重先兆子痫病史的女性和42例先前先兆子痫的女性进行了比较怀孕至少在产后12-24个月。结果。先兆子痫的CIMT高于对照组，FMD低于对照组。我们发现先兆子痫组CIMT与FMD之间存在显着的负相关，但两组之间的脂质分布和胰岛素抵抗没有差异。结论。有严重先兆子痫病史的妇女表现出早期的结构和功能性动脉粥样硬化前血管损害，这可能解释了她们将来患心血管疾病的风险更高。

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