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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Quantitative assessment of power Doppler mapping in the detection of renal allograft complications.
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Quantitative assessment of power Doppler mapping in the detection of renal allograft complications.

机译：能量多普勒定位在肾脏同种异体移植并发症检测中的定量评估。

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PURPOSE: We evaluated the usefulness of power Doppler (PD) imaging with a quantitative parameter in the identification of renal transplant complications. METHODS: One hundred eight transplanted kidneys were subjected to PD examinations. The blood flow area ratio (BFAR), defined as the percentage of the area of color pixels within a given cross-sectional area placed over a region of a transplanted kidney, was measured using built-in color histogram software and used as a quantitative parameter for evaluating the status of allograft blood perfusion. The mean BFARs in the normal, acute rejection (AR), acute tubular necrosis (ATN), chronic rejection (CR), and cytomegalovirus infection (CMV) groups were compared. RESULTS: The BFAR in the normal group tended to decrease gradually with the time interval since transplantation, but the mean value, 0.68+/-0.08, was significantly higher than that in the complication groups: AR, 0.43+/-0.18; ATN, 0.43+/-0.14; CR, 0.15+/-0.14; and CMV, 0.36+/-0.10 (p < 0.01 for all). When a BFAR of 0.60 or greater was used as the diagnostic criterion for normal allografts, a sensitivity, specificity, and accuracy of more than 90% could be achieved in the diagnosis of complications. However, owing to overlapping BFARs among the complication groups, the BFAR alone had a limited ability to differentiate the types of complications. CONCLUSIONS: Although PD imaging has some limitations in identifying the nature of renal allograft complications, the use of the quantitative parameter BFAR in the PD assessment of renal allografts may be useful in detecting complications. Further studies are needed to explore the BFAR's clinical value.
机译：目的：我们评估了带有定量参数的功率多普勒（PD）成像在鉴定肾移植并发症中的有用性。方法：对108例移植肾进行了PD检查。使用内置的颜色直方图软件测量血流面积比（BFAR），它是指放置在移植肾脏区域上的给定横截面内的彩色像素面积的百分比。用于评估同种异体血液灌注状况。比较了正常，急性排斥（AR），急性肾小管坏死（ATN），慢性排斥（CR）和巨细胞病毒感染（CMV）组的平均BFAR。结果：正常组的BFAR有随移植时间间隔逐渐降低的趋势，但平均值0.68 +/- 0.08显着高于并发症组：AR：0.43 +/- 0.18。 ATN，0.43 +/- 0.14; CR，0.15 +/- 0.14;和CMV为0.36 +/- 0.10（所有p <0.01）。如果将BFAR设为0.60或更高作为正常同种异体移植物的诊断标准，则在诊断并发症时可以达到90％以上的敏感性，特异性和准确性。但是，由于并发症组之间的BFAR重叠，因此仅BFAR区分并发症类型的能力有限。结论：尽管PD成像在识别肾移植物并发症的性质方面有一定的局限性，但在肾移植物PD评估中使用定量参数BFAR可能有助于检测并发症。需要进一步研究以探索BFAR的临床价值。

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