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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Echocardiographic abnormalities in a cohort of Chinese patients with systemic lupus erythematosus--a retrospective analysis of eighty-five cases.
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Echocardiographic abnormalities in a cohort of Chinese patients with systemic lupus erythematosus--a retrospective analysis of eighty-five cases.

机译：一组中国系统性红斑狼疮患者的超声心动图异常-回顾分析85例。

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OBJECTIVE: To investigate echocardiographic abnormalities in a cohort of Chinese patients with systemic lupus erythematosus (SLE). METHODS: Eighty-five SLE patients who were hospitalized at our institution from January 2008 to June 2009 were included. Their clinical manifestations, electrocardiogram, chest x-ray, CT scan, and echocardiographic data were analyzed in relation to age, disease duration, and SLE disease activity index (SLEDAI). RESULTS: Echocardiography showed abnormalities in 53 patients (62.35%), involving valves in 56.5% (n = 48), pericardium in 25.9%, left and right ventricle enlargement in 17.65% and 1.18%, respectively, and auricle in 10.59% and 1.18% of the patients, respectively. The left ventricle showed decreased compliance in 10.29%, impaired relaxation in 14.12%, and abnormal wall motion in 42.35% of the patients. Interventricular septum thickness, left ventricular posterior wall thickness, and isovolumic relaxation time were positively correlated with age (r = 0.42, 0.33, and 0.39, respectively, p < 0.01 for all variables), and disease duration (r = 0.22, 0.21, and 0.32, respectively; p < 0.05). Left atrial and ventricular size were correlated with age (r = 0.32 and 0.41, p > 0.01) and SLEDAI (p < 0.05). CONCLUSIONS: Cardiac, especially valvular abnormalities are common in SLE patients and increase with age and disease duration and activity. Inclusion of echocardiography in the clinical evaluation of SLE patients could help identify an important subset of patients with cardiac abnormalities.
机译：目的：调查中国系统性红斑狼疮（SLE）患者队列的超声心动图异常。方法：纳入2008年1月至2009年6月在我院住院的85例SLE患者。他们的临床表现，心电图，胸部X线，CT扫描和超声心动图数据进行了分析与年龄，病程和SLE疾病活动指数（SLEDAI）。结果：超声心动图检查发现53例患者（62.35％）异常，其中瓣膜占56.5％（n = 48），心包占25.9％，左，右心室扩大分别占17.65％和1.18％，耳廓占10.59％和1.18分别为％的患者。左心室的顺应性降低了10.29％，放松受损减弱了14.12％，壁运动异常的患者占42.35％。室间隔厚度，左室后壁厚度和等容舒张时间与年龄（所有变量分别为r = 0.42、0.33和0.39，p <0.01）和疾病持续时间（r = 0.22、0.21和分别为0.32; p <0.05）。左心房和心室大小与年龄（r = 0.32和0.41，p> 0.01）和SLEDAI（p <0.05）相关。结论：SLE患者常见于心脏，尤其是瓣膜异常，并随年龄，疾病持续时间和活动而增加。在SLE患者的临床评估中包括超声心动图检查可能有助于确定心脏异常患者的重要子集。

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