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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Evaluation of finger joint synovial vascularity in patients with rheumatoid arthritis using contrast-enhanced ultrasound with water immersion and a stabilized probe
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Evaluation of finger joint synovial vascularity in patients with rheumatoid arthritis using contrast-enhanced ultrasound with water immersion and a stabilized probe

机译：超声造影和水浸增强探头对类风湿关节炎患者手指关节滑膜血管的评价

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Purpose.: To assess synovial microvascularity in finger joints with rheumatoid arthritis (RA) by contrast-enhanced ultrasound (CEUS), distinguishing between cases of active disease and those in remission; to standardize the technique for software analysis. Methods.: Fifty-two finger joints of RA patients (26 with active disease and 26 in remission) were immersed in water and examined by CEUS using a fixed probe. Signal intensity curves were calculated with the software. Results.: Contrast enhancement was detectable in all 26 patients with active RA (100%), but not in 25 of 26 patients in remission (96%); one of the latter patients (4%) showed minimal enhancement. The method's sensitivity and specificity in distinguishing active disease from remission were 100% and 96%. The grades of synovial enhancement correlated with clinical disease activity and software flow parameters. The peak contrast levels correlated with clinical activity, a peak of 9% representing the cutoff between remission and active disease. Conclusions.: CEUS with a fixed probe on finger joints immersed in water detected synovial vascularization in RA, producing results suitable for standardized software analysis and avoiding artifacts.
机译：目的：通过对比增强超声（CEUS）评估风湿性关节炎（RA）手指关节的滑膜微血管分布，以区分活动性疾病和缓解性疾病;标准化软件分析技术。方法：将RA患者的52个手指关节（26例活动性疾病和26例缓解状态）浸入水中，并使用固定探头通过CEUS检查。使用软件计算信号强度曲线。结果：在活动性RA的所有26例患者中（100％）可检测到对比度增强，但在缓解的26例患者中有25例（96％）未检测到对比度增强;后一例患者（4％）表现出最小的增强。该方法区分活动性疾病和缓解性疾病的敏感性和特异性分别为100％和96％。滑膜增强的等级与临床疾病活动和软件流程参数相关。峰值对比水平与临床活动相关，峰值为9％代表缓解和活动性疾病之间的界限。结论：CEUS的手指关节固定探针浸入水中，可检测出RA中的滑膜血管形成，产生适合标准化软件分析并避免伪影的结果。

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