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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Real-time three-dimensional echocardiographic evaluation of left ventricular systolic synchronicity in patients with chronic heart failure: Comparison with tissue doppler imaging
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Real-time three-dimensional echocardiographic evaluation of left ventricular systolic synchronicity in patients with chronic heart failure: Comparison with tissue doppler imaging

机译：实时三维超声心动图评估慢性心力衰竭患者左心室收缩同步性：与组织多普勒成像的比较

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Background.: To investigate the clinical value of real-time three-dimensional echocardiography (RT-3DE) for assessing of left ventricular systolic synchronicity. Methods.: Thirty healthy volunteers and 62 patients with congestive heart failure (CHF) were enrolled. The SD of time to peak systolic motion (TDI-Ts12-SD) was measured with tissue Doppler imaging in 12 myocardial segments. The SD and maximal difference of the time to minimal systolic volume (Tmsv) between 16, 12, or 6 myocardial segments, expressed as a percentage of cardiac cycle duration, were measured with RT-3DE and labeled Tmsv16-SD%, Tmsv12-SD%, Tmsv6-SD%, Tmsv16-D%, Tmsv12-D%, and Tmsv6-D%, respectively. The Spearman coefficient and Kappa value were calculated, and Bland-Altman analysis was performed to investigate the correlation and agreement between the two methods. Tmsv values were compared with ejection fraction (EF). Results.: There was a moderately positive (p< 0.01) correlation between TDI-Ts12-SD and Tmsv16-SD%, Tmsv12-SD%, Tmsv16-D%, and Tmsv12-D% (r = 0.65, 0.64, and 0.65, respectively, with Kappa values of 0.66, 0.65, 0.72, and 0.74, respectively, p< 0.01). Tmsv16-SD%, Tmsv12-SD%, and Tmsv12-D% were significantly different between CHF patients with EF ≤ 35% and those with EF > 35%. Conclusions.: RT-3DE can be used in patients with CHF to quantify left ventricular mechanical dyssynchrony. Tmsv12-SD% and Tmsv12-D% were the best indices of left ventricular systolic synchronicity in relation to the severity of CHF as evaluated from EF.
机译：背景：目的：研究实时三维超声心动图（RT-3DE）在评估左心室收缩同步性的临床价值。方法：30名健康志愿者和62名充血性心力衰竭（CHF）患者入选。收缩运动峰值时间（TDI-Ts12-SD）通过组织多普勒成像仪在12个心肌节段中测量。用RT-3DE和标记的Tmsv16-SD％，Tmsv12-SD测量了16和12或6个心肌节段之间的SD和最小收缩期时间（Tmsv）的最大差值，以心动周期的百分比表示。百分比，Tmsv6-SD％，Tmsv16-D％，Tmsv12-D％和Tmsv6-D％。计算Spearman系数和Kappa值，并进行Bland-Altman分析以研究两种方法之间的相关性和一致性。将Tmsv值与射血分数（EF）进行比较。结果：TDI-Ts12-SD与Tmsv16-SD％，Tmsv12-SD％，Tmsv16-D％和Tmsv12-D％之间存在中等正相关（p <0.01）（r = 0.65、0.64和0.65 ，其Kappa值分别为0.66、0.65、0.72和0.74，p <0.01）。 EF≤35％的CHF患者和EF> 35％的CHF患者的Tmsv16-SD％，Tmsv12-SD％和Tmsv12-D％显着不同。结论：RT-3DE可用于CHF患者以量化左心室机械不同步。根据EF评估，Tmsv12-SD％和Tmsv12-D％是相对于CHF严重程度的左心室收缩同步性的最佳指标。

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