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First trimester transabdominal chorionic villus sampling-does the needle matter?

机译:早孕期经腹绒毛膜绒毛取样-针头重要吗?

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Purpose: To compare first-trimester transabdominal chorionic villus samples (TA-CVS) when obtained by 20-gauge amniocentesis versus lancet needles. Methods: This is a retrospective study of all women with viable singleton pregnancies undergoing TA-CVS from 01/01/2009 to 03/31/2011. All CVS were performed by a single operator using a freehand technique and amniocentesis needles from 01/01/2009 to 08/31/2010 and lancet needles from 09/01/2010 to 03/31/2011. All samples were processed by the same laboratory. Results: There were no differences between groups regarding maternal age, weight, gestational age at CVS, indication for CVS, uterine position, or placental location. Lancet needles were associated with significantly larger samples (median 18 [range 3-40] versus 7 [range 1-33] mg, p < 0.0001), more successful in situ hybridization (96% versus 74.2%, p = 0.03), and faster result reporting (median 7 [range 5-12] versus 9 [range 6-26] days, p = 0.002). Conclusions: Needle type may be clinically important when selecting 20-gauge TA-CVS needles.
机译:目的:比较通过20号羊膜穿刺术与刺血针获得的头三个月经腹绒毛膜绒毛样本(TA-CVS)。方法:这是一项回顾性研究,对所有从2009年1月1日至2011年3月31日接受TA-CVS的可行单胎妊娠妇女进行研究。所有CVS均由一名操作员使用徒手技术进行,从2009年1月1日至2010年8月31日使用羊膜穿刺针,从2010年9月1日至2011年3月31日使用柳叶刀针。所有样品均由同一实验室处理。结果:两组之间在产妇年龄,体重,CVS的胎龄,CVS的指征,子宫位置或胎盘位置方面没有差异。刺血针与明显更大的样品相关(中位18 [范围3-40]对7 [范围1-33] mg,p <0.0001),更成功的原位杂交(96%对74.2%,p = 0.03)和结果报告速度更快(中位数7 [范围5-12]与9 [范围6-26]天,p = 0.002)。结论:选择20号TA-CVS针头时,针头类型可能在临床上很重要。

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