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Perinatal outcomes after sonographic detection of isolated short femur in the second trimester

机译:在妊娠中期超声检查发现孤立的短股骨后的围产期结局

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Purpose: To determine the association of fetal isolated short femur in the second-trimester ultrasound (US) examination with perinatal outcomes such as small-for-gestational age (SGA) and low-birth weight (LBW) neonates. Methods: This is a retrospective cohort study in fetuses routinely assessed by US examination at 18 to 24 weeks during 2006-2009. A fetal isolated short femur was defined as femur length below the 5th percentile and with no chromosomal or structural abnormalities. Fetuses with abdominal circumference below the 5th percentile at the time of US examination were excluded. Each case of short femur was matched with three controls according to gestational age at the time of the US examination. Results: Sixty-one fetuses met the inclusion criteria. Both the group of women carrying a fetus with isolated short femur and that of women carrying a fetus with normal femur length had similar general and obstetric characteristics. Women carrying a fetus with isolated short femur were significantly more likely to deliver a SGA neonate (19.7% versus 8.7%, p < 0.05) and a LBW neonate (19.7% versus 7.1%, p < 0.05) than women carrying a fetus with normal femur length. Logistic regression analysis found odds ratios for SGA and LBW of 2.6 (95% confidence interval, 1.1-5.9) and 2.9 (95% confidence interval, 1.2-7.1), respectively. Conclusions: Isolated short femur in the second-trimester US examination is associated with a subsequent delivery of SGA and LBW neonates.
机译:目的:确定孕中期超声(US)检查中胎儿孤立的短股骨与围产期结局(如小胎龄(SGA)和低出生体重(LBW)的新生儿)的关联。方法:这是一项回顾性队列研究,在2006-2009年间18到24周通过美国检查常规评估了胎儿。胎儿孤立的短股骨定义为股骨长度低于第5个百分点,且没有染色体或结构异常。在US检查时,腹围低于5个百分点的胎儿被排除在外。在美国检查时,根据胎龄,每例短股骨均与三个对照相匹配。结果:61例胎儿符合纳入标准。携带具有孤立的短股骨的胎儿的妇女群体和携带正常股骨长度的胎儿的妇女群体具有相似的一般和产科特征。携带孤立的股骨短的胎儿的妇女比携带正常胎儿的妇女分娩SGA新生儿(19.7%vs.8.7%,p <0.05)和LBW新生儿(19.7%vs 7.1%,p <0.05)的可能性更高。股骨长。 Logistic回归分析发现SGA和LBW的优势比分别为2.6(95%置信区间1.1-5.9)和2.9(95%置信区间1.2-7.1)。结论:美国中期妊娠中孤立的短股骨与随后的SGA和LBW新生儿分娩有关。

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