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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Clinical outcome and follow-up of sonographically suspected in utero urinary tract anomalies.
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Clinical outcome and follow-up of sonographically suspected in utero urinary tract anomalies.

机译：宫腔泌尿系统异常的超声检查的临床结果和随访。

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摘要

PURPOSE: We determined the outcome of pregnancy and long-term renal function in cases of sonographically detected fetal urinary tract anomalies (UTAs). METHODS: This was a retrospective cohort study done at an academic hospital (tertiary referral center). All records of prenatal sonographic examinations done between January 1985 and October 1994 that indicated a suspicion for UTA were examined for perinatal mortality, postnatal confirmation of sonographic diagnosis, postnatal management, and calculated creatinine clearance to determine the ultimate renal function. RESULTS: Of 99 cases with suspected UTAs, 28 pregnancies were terminated because the UTA was considered fatal, and 32 fetuses died perinatally. Twenty-one children are alive with good renal function, 4 with moderate renal function, and 2 with poor renal function. The prenatal diagnosis was not confirmed after birth in 12 children, all of whom are alive with good renal function. The prognosis for prenatally suspected UTA was worse in cases of bilateral involvement and in cases with associated multiple malformations. CONCLUSIONS: The prognosis of prenatally diagnosed UTAs depends on the specific anomaly suspected. Abnormal karyotype, other associated malformations, and bilateral involvement are unfavorable determinants of the prognosis in individual cases.
机译：目的：我们确定了超声检查发现的胎儿泌尿道异常（UTA）病例的妊娠结局和长期肾功能。方法：这是在学术医院（三级转诊中心）进行的一项回顾性队列研究。在1985年1月至1994年10月之间进行的所有产前超声检查记录均显示怀疑患有UTA，检查了围产期死亡率，产后超声检查确诊，产后管理和计算的肌酐清除率，以确定最终的肾功能。结果：在99例疑似UTA患者中，有28例因终止UTA致死而终止妊娠，有32例胎儿在围产期死亡。存活的儿童中有21名肾功能良好，4名中度肾功能，2名肾功能较差。出生后未确诊产前诊断的12名儿童，所有这些儿童都还活着，并且肾功能良好。在双侧受累和伴有多种畸形的情况下，产前疑似UTA的预后较差。结论：产前诊断的UTA的预后取决于可疑的具体异常情况。核型异常，其他相关的畸形和双侧受累是个别病例预后的不利决定因素。

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