首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >Photodynamic therapy of cerebral glioma - a review. Part II - clinical studies.
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Photodynamic therapy of cerebral glioma - a review. Part II - clinical studies.

机译:脑胶质瘤的光动力疗法-综述。第二部分-临床研究。

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摘要

Photodynamic therapy (PDT) is a binary treatment modality that has been used to treat malignant brain tumours for 25 years. The treatment involves the selective uptake of a photosensitizer (PS) by the tumour cells followed by irradiation of the tumour with light of the appropriate wavelength to excite and activate the PS resulting in selective tumour destruction and is a potentially valuable adjunct to surgical excision and other conventional therapies. PDT has undergone extensive laboratory studies and clinical trials with a variety of PS and tumour models. These are discussed with reference mainly to clinical studies involving the PDT of brain tumours.
机译:光动力疗法(PDT)是一种二元治疗方式,已用于治疗恶性脑肿瘤25年。该治疗涉及肿瘤细胞选择性吸收光敏剂(PS),然后用适当波长的光照射肿瘤以激发和激活PS,从而导致选择性的肿瘤破坏,这可能是手术切除和其他治疗的潜在有价值的辅助手段常规疗法。 PDT已针对各种PS和肿瘤模型进行了广泛的实验室研究和临床试验。讨论这些主要参考涉及脑肿瘤PDT的临床研究。

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