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首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >A comparison of the hemodynamic effects of flow diverters on wide-necked and narrow-necked cerebral aneurysms
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A comparison of the hemodynamic effects of flow diverters on wide-necked and narrow-necked cerebral aneurysms

机译：分流器对宽颈和窄颈脑动脉瘤的血流动力学影响的比较

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Flow diverters (FD), a new generation of intracranial stents with a low porosity mesh, have been applied as an alternative treatment for intracranial aneurysms. However, their efficacy varies among aneurysms of different morphology. In this study, computational fluid dynamic simulations were performed to examine the influence of an FD on the hemodynamics of wide-necked and narrow-necked cerebral aneurysms. An FD with 70% porosity mesh was deployed across the neck of an ideal narrow-necked and wide-neck aneurysm model. The hemodynamics at the aneurysmal sac were changed markedly in both models. At the inflow portion of the aneurysm neck of the narrow-necked aneurysm, the peak velocity and wall shear stress were reduced by 84% and 91%, respectively. By comparison, in the wide-necked aneurysm model, the results were 47% and 21%, respectively. This study demonstrates that the FD markedly altered the hemodynamic conditions inside intracranial aneurysms, depending on aneurysm morphology. Therefore, hemodynamic modifications should be individually designed for aneurysms with different morphology.
机译：分流器（FD）是新一代的低孔隙度网状颅内支架，已被用作颅内动脉瘤的替代治疗方法。然而，它们的功效在不同形态的动脉瘤之间有所不同。在这项研究中，进行了计算流体动力学模拟，以检查FD对宽颈和窄颈脑动脉瘤的血流动力学的影响。在理想的窄颈和宽颈动脉瘤模型的脖子上展开具有70％孔隙率网格的FD。在两种模型中，动脉瘤囊的血流动力学都发生了明显变化。在窄颈动脉瘤的动脉瘤颈部的流入部分，峰值速度和壁切应力分别降低了84％和91％。相比之下，在宽颈动脉瘤模型中，结果分别为47％和21％。这项研究表明，FD显着改变了颅内动脉瘤内的血液动力学状况，这取决于动脉瘤的形态。因此，应针对具有不同形态的动脉瘤分别设计血液动力学修饰。

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