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首页> 外文期刊>Clinical chemistry and laboratory medicine: CCLM >Glutathione peroxidase activity and serum selenium concentration in intrinsic asthmatic patients.
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Glutathione peroxidase activity and serum selenium concentration in intrinsic asthmatic patients.

机译：内在哮喘患者的谷胱甘肽过氧化物酶活性和血清硒浓度。

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摘要

Serum glutathione peroxidase (GSH-Px) activity and selenium concentration were compared in intrinsic asthmatic patients and non-asthmatic control subjects. Serum GSH-Px activity and selenium concentration were assessed in 46 asthmatic patients and 75 age- and sex-matched non-asthmatic subjects by spectrophotometric assay. Mean serum GSH-Px activity was lower in intrinsic asthmatic subjects (9.4 +/- 2.6 pmol NADPH oxidized/min/g of protein) than in non-asthmatic subjects (16.3 +/- 2.9 pmol NADPH oxidized/min/g of protein). Mean serum selenium was lower in intrinsic asthmatic subjects (1.15 +/- 0.23 microM) than in non-asthmatic subjects (1.98 +/- 0.27 microM). Asthmatic patients have significantly lower concentration of selenium and GSH-Px activity measured in serum.
机译：比较了内在哮喘患者和非哮喘对照组的血清谷胱甘肽过氧化物酶（GSH-Px）活性和硒浓度。通过分光光度法测定了46例哮喘患者以及75例年龄和性别相匹配的非哮喘患者的血清GSH-Px活性和硒浓度。内在哮喘受试者的平均血清GSH-Px活性（9.4 +/- 2.6 pmol NADPH氧化/ min / g蛋白质）低于非哮喘受试者（16.3 +/- 2.9 pmol NADPH氧化/ min / g蛋白质） 。内在哮喘受试者的平均血清硒水平（1.15 +/- 0.23 microM）低于非哮喘受试者（1.98 +/- 0.27 microM）。哮喘患者血清中的硒浓度和GSH-Px活性明显降低。

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