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首页> 外文期刊>Journal of digital imaging: the official journal of the Society for Computer Applications in Radiology >Computer-aided diagnosis of proliferative diabetic retinopathy via modeling of the major temporal arcade in retinal fundus images
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Computer-aided diagnosis of proliferative diabetic retinopathy via modeling of the major temporal arcade in retinal fundus images

机译：通过对视网膜眼底图像中的主要颞弓进行​​建模，计算机辅助诊断增生性糖尿病视网膜病变

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摘要

Monitoring the openness of the major temporal arcade (MTA) and how it changes over time could facilitate diagnosis and treatment of proliferative diabetic retinopathy (PDR). We present methods for user-guided semiautomated modeling and measurement of the openness of the MTA based on Gabor filters for the detection of retinal vessels, morphological image processing, and a form of the generalized Hough transform for the detection of parabolas. The methods, implemented via a graphical user interface, were tested with retinal fundus images of 11 normal individuals and 11 patients with PDR in the present pilot study on potential clinical application. A method of arcade angle measurement was used for comparative analysis. The results using the openness parameters of single- and dual-parabolic models as well as the arcade angle measurements indicate areas under the receiver operating characteristics of A z = 0.87, 0.82, and 0.80, respectively. The proposed methods are expected to facilitate quantitative analysis of the architecture of the MTA, as well as assist in detection and diagnosis of PDR.
机译：监测主要颞弓（MTA）的开放性及其随时间的变化可促进增生性糖尿病性视网膜病变（PDR）的诊断和治疗。我们提出了基于Gabor滤波器的视网膜光学血管检测，形态学图像处理以及一种用于检测抛物线的广义Hough变换形式的用户指导的半自动建模和MTA开放度测量方法。通过图形用户界面实现的方法，在当前关于潜在临床应用的初步研究中，以11名正常人和11名PDR患者的眼底图像进行了测试。使用拱角测量方法进行比较分析。使用单抛物线模型和双抛物线模型的开放性参数以及拱形角测量结果表明，接收器工作特性下的面积分别为A z = 0.87、0.82和0.80。预期所提出的方法将有助于定量分析MTA的体系结构，并有助于检测和诊断PDR。

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