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首页> 外文期刊>Journal of digital imaging: the official journal of the Society for Computer Applications in Radiology >Impact of a computer-aided detection (CAD) system integrated into a picture archiving and communication system (PACS) on reader sensitivity and efficiency for the detection of lung nodules in thoracic CT exams
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Impact of a computer-aided detection (CAD) system integrated into a picture archiving and communication system (PACS) on reader sensitivity and efficiency for the detection of lung nodules in thoracic CT exams

机译：集成到图片存档和通信系统（PACS）中的计算机辅助检测（CAD）系统对在胸部CT检查中检测肺结节的阅读器灵敏度和效率的影响

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The objective of this study is to assess the impact on nodule detection and efficiency using a computer-aided detection (CAD) device seamlessly integrated into a commercially available picture archiving and communication system (PACS). Forty-eight consecutive low-dose thoracic computed tomography studies were retrospectively included from an ongoing multi-institutional screening study. CAD results were sent to PACS as a separate image series for each study. Five fellowship-trained thoracic radiologists interpreted each case first on contiguous 5 mm sections, then evaluated the CAD output series (with CAD marks on corresponding axial sections). The standard of reference was based on three-reader agreement with expert adjudication. The time to interpret CAD marking was automatically recorded. A total of 134 true-positive nodules, measuring 3 mm and larger were included in our study; with 85≥4 and 50≥5 mmin size. Readers detection improved significantly in each size category when using CAD, respectively, from 44 to 57 % for≥3 mm, 48 to 61%for≥4 mm, and 44 to 60%for ≥5mm.CAD stand-alone sensitivity was 65, 68, and 66 % for nodules ≥3, ≥4, and ≥5 mm, respectively, with CAD significantly increasing the false positives for two readers only. The average time to interpret and annotate a CAD mark was 15.1 s, after localizing it in the original image series. The integration of CAD into PACS increases reader sensitivity with minimal impact on interpretation time and supports such implementation into daily clinical practice.
机译：这项研究的目的是使用计算机辅助检测（CAD）设备无缝集成到市售图片存档和通信系统（PACS）中，评估对结核检测和效率的影响。一项正在进行的多机构筛查研究回顾性地纳入了48例连续的低剂量胸部计算机断层扫描研究。 CAD结果作为每个研究的单独图像系列发送到PACS。五名经过研究金培训的胸腔放射科医生首先在连续的5毫米截面上解释每种情况，然后评估CAD输出序列（在相应的轴向截面上带有CAD标记）。参考标准基于三级阅读者同意的专家裁决。自动解释了CAD标记的时间。我们的研究中总共包括了134个3毫米及更大的真阳性结节。尺寸为85≥4和50≥5毫米。使用CAD时，每种尺寸类别的读取器检测效果显着提高，≥3mm分别从44％增至57％，≥4mm分别为48％至61％，≥5mm达到44％至60％.CAD独立灵敏度为65，结节≥3，≥4和≥5mm分别为68％和66％，而CAD仅显着增加了两个读取器的假阳性率。将其定位在原始图像系列中后，解释和注释CAD标记的平均时间为15.1 s。将CAD集成到PACS中可以提高阅读器的灵敏度，同时对解释时间的影响最小，并支持将此类实现应用于日常临床实践中。

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