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首页> 外文期刊>Journal of Cranio-Maxillofacial Surgery >Making bone: implant insertion into tissue-engineered bone for maxillary sinus floor augmentation-a preliminary report.
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Making bone: implant insertion into tissue-engineered bone for maxillary sinus floor augmentation-a preliminary report.

机译:制作骨头:将植入物插入组织工程骨头中以进行上颌窦底增强术的初步报告。

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摘要

Autologous, allogenic and alloplastic materials for bony reconstruction in the cranio-maxillofacial area have many drawbacks thus stimulating the on-going search for new (bio-)materials. Whereas cultivated skin and mucosa are already in clinical routine use in head and neck reconstruction, so far there has been no successful clinical application to the best of our knowledge of periosteum-derived, tissue-engineered bone for augmentation of the edentulous posterior maxilla. In a pilot study, augmentation of the posterior maxilla was carried out using a bone matrix derived from mandibular periosteal cells on a polymer fleece. This paper demonstrates fabrication of the matrix, clinical application, and the histological results in two patients. The results suggest that periosteum-derived osteoblasts on a suitable matrix form lamellar bone within 4 months which allows reliable implant insertion.
机译:用于颅颌面部区域中的骨重建的自体,同种异体和同种异体材料具有许多缺点,因此刺激了对新的(生物)材料的持续研究。尽管培养的皮肤和粘膜已经在头颈部重建中进行临床常规使用,但就我们从骨膜衍生的组织工程化骨骼的知识来看,迄今为止,还没有成功的临床应用来增强无牙后颌。在一项前期研究中,使用源自聚合物绒毛上的下颌骨骨膜细胞的骨基质进行后上颌骨的增大。本文展示了两名患者的基质制备,临床应用和组织学结果。结果表明,在合适的基质上,源自骨膜的成骨细胞在4个月内形成了层状骨,从而可以可靠地植入植入物。

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