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首页> 外文期刊>Journal of drugs in dermatology: JDD >Lichenoid drug reaction following influenza vaccination in an HIV-positive patient: A case report and literature review
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Lichenoid drug reaction following influenza vaccination in an HIV-positive patient: A case report and literature review

机译：HIV阳性患者接种流感疫苗后地衣样药物反应：病例报告和文献复习

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摘要

Lichenoid drug reactions to vaccinations are rare but well-documented events. The vast majority of these reported reactions have been triggered by Hepatitis B vaccination (HBV). We describe an impressive generalized lichenoid drug reaction following the influenza vaccination. A 46-year-old African-American woman with a history of treated human immunodeficiency virus (HIV) disease developed a diffuse, pruritic rash one day following vaccination against the influenza virus. Physical exam and histopathology were consistent with a lichenoid drug eruption. This is only the fifth reported case of lichenoid drug reaction, and only the second generalized case, following influenza vaccination. The patient's underlying HIV disease, known to be a risk factor for both cutaneous drug reactions and more severe manifestations of lichen planus, likely predisposed her to this generalized hypersensitivity phenomenon.
机译：地衣类药物对疫苗的反应很少见，但有据可查。这些报告的反应绝大多数是由乙型肝炎疫苗（HBV）触发的。我们描述了在接种流感疫苗后令人印象深刻的广义类苔藓药物反应。一名接受过人类免疫缺陷病毒（HIV）病史治疗的46岁非洲裔美国妇女在接种流感病毒后一天出现了弥漫性瘙痒性皮疹。体格检查和组织病理学与苔藓样药疹一致。这仅是报告的第五例地衣样药物反应病例，也是继流感疫苗接种后的第二例广义病例。患者的潜在HIV疾病已知是皮肤药物反应和扁平苔藓的更严重表现的危险因素，很可能使她易患这种普遍的超敏现象。

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