首页> 外文期刊>Journal of drugs in dermatology: JDD >Intense pulsed light versus advanced fluorescent technology pulsed light for photodamaged skin: a split-face pilot comparison.
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Intense pulsed light versus advanced fluorescent technology pulsed light for photodamaged skin: a split-face pilot comparison.

机译:强烈的脉冲光与先进的荧光技术相比,光致损伤的皮肤具有脉冲光:分体飞行员对比。

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摘要

Intense pulsed light (IPL) has been a popular nonablative treatment of photodamage. A prospective, randomized, controlled, single-blinded, split-face pilot study compared the efficacy and safety of 2 multitechnology broadband pulsed light platform devices: an IPL device (Lumenis One, Lumenis Corporation, Santa Clara, CA) and a fluorescent pulsed light with advanced fluorescent technology (AFT, Harmony System, Alma Lasers, Buffalo Grove, IL) device. Eight volunteer subjects (skin types I-IV) with a 2.0 mean Global Score for Photoaging (scale 0-4) participated in the study. Subjects received 3 to 5 treatments 3 weeks apart in which one side of the face was treated with the IPL device and the other side with the AFT device. During each treatment session, the face received 3 complete passes without anesthesia. Treatment was aggressive and parameters were determined by test spot application. Treatment endpoints were mild erythema. Results were evaluated by clinical observations of the investigator and comparison of pre- and post-treatment photographs by subjects and 2 blinded dermatologists. Blinded evaluators agreed that improvements in dyspigmentation, telangiectasias, erythema, and skin texture were similar on both sides of the face. Subject assessments of discomfort during treatment were also comparable. Adverse effects were not observed.
机译:强烈脉冲光(IPL)已成为光损伤的流行非烧蚀治疗方法。一项前瞻性,随机,对照,单盲,双瓣先导研究比较了2种多技术宽带脉冲光平台设备的功效和安全性:IPL设备(Lumenis One,Lumenis Corporation,Santa Clara,CA)和荧光脉冲光具有先进的荧光技术(AFT,Harmony System,Alma Lasers,布法罗格鲁夫,伊利诺伊州)的设备。八名志愿受试者(I-IV型皮肤)的平均光老化总得分为2.0(等级0-4)参加了该研究。受试者每3周接受3到5次治疗,其中用IPL设备治疗面部一侧,而使用AFT设备治疗另一侧。在每次治疗过程中,面部均接受了3次完全无麻醉的通行证。治疗是积极的,并且通过测试点应用确定参数。治疗终点为轻度红斑。通过研究人员的临床观察以及受试者和2位盲皮肤科医生对治疗前后照片的比较来评估结果。盲人评估者同意,面部两侧的色素沉着,毛细血管扩张,红斑和皮肤质地的改善相似。受试者对治疗期间不适的评估也具有可比性。未观察到不良反应。

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