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首页> 外文期刊>Journal of cutaneous pathology >Ossified soft tissue leiomyoma in a patient with sickle cell anemia.
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Ossified soft tissue leiomyoma in a patient with sickle cell anemia.

机译：镰状细胞性贫血患者的骨化软组织平滑肌瘤。

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摘要

Osseous metaplasia in leiomyomas is extremely rare. Here, we report the case of an ossified subcutaneous leiomyoma in a 34-year-old African American man with sickle cell thalassemia who presented with a painful nodule of the scapular region, which appeared as a heavily mineralized soft tissue mass on chest radiographs. Histopathologic and immunohistochemical examination of the resected nodule revealed a benign soft tissue leiomyoma composed of intersecting fascicles of spindle cells that strongly expressed smooth muscle actin and caldesmon. Extensive intratumoral calcification and ossification were noticed. Only eight cases of ossified leiomyoma have been reported, of which two arose in the deep soft tissue.
机译：平滑肌瘤骨化生极为罕见。在这里，我们报道了一个患有镰状细胞地中海贫血的34岁非洲裔美国人的骨化皮下平滑肌瘤的病例，他出现了肩骨区域的结节性疼痛，在胸部X光片上表现为严重矿化的软组织肿块。切除结节的组织病理学和免疫组织化学检查显示良性软组织平滑肌瘤由梭形细胞的交叉束组成，其强烈表达平滑肌肌动蛋白和卡尔德斯蒙。注意到广泛的肿瘤内钙化和骨化。仅报道了8例骨化平滑肌瘤，其中2例出现在深部软组织中。

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