...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of drug assessment >A pharmacoeconomic evaluation of piperacillin/tazobactam versus meropenem in the treatment of adult febrile neutropenia
【24h】

A pharmacoeconomic evaluation of piperacillin/tazobactam versus meropenem in the treatment of adult febrile neutropenia

机译：哌拉西林/他唑巴坦与美罗培南联合治疗成人发热性中性粒细胞减少症的药物经济学评价

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A study involving 80 patients has established the safety and efficacy of piperacillin/tazobactam (PT) versus meropenem (ME) in the treatment of febrile neutropenia. The study reported here assessed 78 of 80 patients and has shown that the total antimicrobial costs of the two study arms were very similar, except for the acquisition costs of the two study drugs and the antimicrobial prescription costs in the post-study period. The total antimicrobial costs for the PT and ME arms for the prestudy, study and post-study periods, respectively, were: PT zeta2,052.22/ME zeta1,140.49,PT zeta28,726.57/ME zeta49,954.80 and PT zeta10,863.45/ME zeta3,542.27. A detailed review of these post-study antimicrobial prescriptions demonstrated that cost differences lay in the prescription of antibacterial antimicrobials. This post-study difference lay in the additional prescription of 145.15 defined daily doses of antibacterial antimicrobials in the PT arm and were ascribed, in the main, to teicoplanin, vancomycin, imipenem, metronidazole and ciprofloxacin. Forty-three percent of the total post-study antibacterial cost was due to the use of imipenem in eight patients in the PT arm.
机译：一项涉及80位患者的研究确定了哌拉西林/他唑巴坦（PT）与美罗培南（ME）在治疗发热性中性粒细胞减少症中的安全性和有效性。此处的研究报告评估了80位患者中的78位，并显示两个研究部门的总抗菌药物成本非常相似，除了两种研究药物的购置成本和研究后的抗菌药物处方成本。在研究前，研究和研究后期间，PT和ME部门的总抗菌费用分别为：PT zeta2,052.22 / ME zeta1,140.49，PT zeta28,726.57 / ME zeta49,954.80和PT zeta10,863.45 / ME zeta3,542.27。对这些研究后抗菌药物处方的详细审查表明，成本差异在于抗菌药物的处方。研究后的差异在于在PT臂上规定的每日抗菌剂量为145.15，这主要归因于替考拉宁，万古霉素，亚胺培南，甲硝唑和环丙沙星。研究后抗菌药物总成本的百分之四十三是由于在PT组中有8名患者使用了亚胺培南。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号