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首页> 外文期刊>Journal of cosmetic dermatology >Contact sensitization to cosmetic series of allergens in a general population in Beijing.
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Contact sensitization to cosmetic series of allergens in a general population in Beijing.

机译：北京普通人群对化妆品系列过敏原的接触致敏。

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摘要

Cosmetic allergic contact dermatitis (CACD) due to common cosmetic allergens in standard series has been extensively studied; however, the prevalence of contact allergy to other cosmetic allergens other than those in standard series is largely unknown. In this study, the frequency of contact sensitization to a European cosmetic series of allergens (Chemotechnique Diagnostics, Vellinge, Sweden) in healthy university student volunteers were detected in Beijing. Of 201 students studied, fifty-eight exhibited positive results, and 9 of them reported had cosmetics related dermatitis previously. The total positivity rate was not correlated to gender. The leading allergens were thimerosal (19.4%), shellac (3.0%), cocamidopropyl betaine (2.0%), hexamethylenetetramine (1.5%), dodecyl gallate (1.5%), hexahydro-1,3,5-tris-(2-hydroxyethyl)triazine (1.0%) and methyldibromo glutaronitrile (1.0%). The positivity rate of thimerosal patch test in men (9.8%) was lower than that of women (23.6%, P??0.05, Chi square test). These results suggested that some cosmetic-related contact allergies may be missed by just testing patients with the European standard series or T.R.U.E. test system only, we recommend shellac, cocamidopropyl betaine, hexamethylenetetramine and dodecyl gallate as the additionally candidates for patch testing in patients with suspected CACD.
机译：由于标准系列中常见的化妆品过敏原，导致了化妆品过敏性接触性皮炎（CACD）的广泛研究。但是，与标准系列以外的其他化妆品过敏原相比，接触过敏的患病率尚不清楚。在这项研究中，在北京检测了健康的大学生志愿者对欧洲一系列化妆品过敏原（Chemotechnique Diagnostics，Vellinge，瑞典）的接触致敏频率。在研究的201名学生中，有58名学生表现出积极的结果，其中9名学生以前报告过化妆品相关的皮炎。总阳性率与性别无关。主要的过敏原为硫柳汞（19.4％），虫胶（3.0％），椰油酰胺基丙基甜菜碱（2.0％），六亚甲基四胺（1.5％），十二烷基没食子酸酯（1.5％），六氢-1,3,5-三-（2-羟乙基） ）三嗪（1.0％）和甲基二溴戊二腈（1.0％）。男性的硫柳汞斑试验阳性率（9.8％）低于女性（23.6％，P≤0.05，卡方检验），但其他化妆品过敏原的患病率与男性相比无差异。妇女（P≥0.05，卡方检验）。这些结果表明，仅测试具有欧洲标准系列或T.R.U.E.的患者可能会错过一些与化妆品相关的接触过敏。仅在测试系统中，我们建议使用虫胶，椰油酰胺丙基甜菜碱，六亚甲基四胺和没食子酸十二烷基酯作为疑似CACD患者的斑贴测试的其他候选药物。

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