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Interpreting negative virus results from highly treated water

机译:解释阴性病毒来自经过高度处理的水

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Highly treated waters often contain viruses at concentration levels too low to detect. This paper describes a method for drawing inferences about the concentration of viruses in treated water when very few or none are detected in collected samples. The approach uses a volume-varying version of the negative binomial distribution to construct one-sided confidence intervals about the mean virus concentration. Information on the presence of viruses prior to treatment (i.e., when densities are high enough to measure) is used to estimate parameters for the model. Samples are provided based on measurements from three southern California wastewater-treatment plants. Based on 93,679 L of tertiary treated sewage effluent, confidence intervals for virus concentrations for Pomona, Calif., ranged from 0 to 2.68.10(-5) plaque forming units (PFU) per liter at the 50% confidence level to 0 to 5.83.10(-4) PFU/L at the 95% confidence level. These values are considerably above the risk-based public health goal that is being used to regulate viruses in drinking water (2.22.10(-7) PFU/L). Direct measurements to demonstrate treatment to drinking water quality are therefore impracticable.
机译:经过高度处理的水通常含有的病毒浓度太低而无法检测。本文描述了一种方法,当收集的样品中很少或根本没有检测到时,可以推断出处理水中病毒的浓度。该方法使用负二项式分布的体积变化形式来构造有关平均病毒浓度的单边置信区间。在处理之前(即,当密度足够高以进行测量时)有关病毒存在的信息用于估计模型的参数。根据来自南加州三个废水处理厂的测量结果提供了样品。基于93,679升经三级处理的污水,加州波莫纳的病毒浓度置信区间为每升0至2.68.10(-5)噬菌斑形成单位(PFU),置信度为50%至0至5.83。 .10(-4)PFU / L,置信度为95%。这些值大大高于用于调节饮用水中病毒的基于风险的公共卫生目标(2.22.10(-7)PFU / L)。因此,无法直接测量以证明对饮用水水质的处理。

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