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首页> 外文期刊>Journal of enzyme inhibition and medicinal chemistry. >Erratum: Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: An in vitro study (Journal of Enzyme Inhibition and Medicinal Chemistry (2012) 27: 5 (641-645)
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Erratum: Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: An in vitro study (Journal of Enzyme Inhibition and Medicinal Chemistry (2012) 27: 5 (641-645)

机译：勘误：某些药物对人脐血红细胞碳酸酐酶I和II的影响：一项体外研究（酶抑制与药物化学杂志（2012）27：5（641-645）

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Objective. Although 70-80% of panic disorder patients use primary care to obtain mental health services, relatively few studies have examined panic patients in this setting. This study aimed to examine both the lifetime and current comorbid psychiatric disorders associated with panic disorder in primary care, the duration and severity of the disorder, and the sociodemographic factors associated with it. Design. Patients were screened for panic disorder. Panic disorder and the comorbid disorders were determined using the Structured Clinical Interview for DSM-IV Axis I and II. Setting. Eight different health care centers in primary care in the city of Espoo. Subjects. Finnish-speaking, between 18 and 65 years of age. Main outcome measures. Comorbid psychiatric disorders, the duration and severity of the disorder, and the sociodemographic factors. Results. A sample of 49 panic disorder patients and 44 patients with no current psychiatric diagnosis were identified; 98% of panic disorder patients had at least one comorbid lifetime DSM-IV Axis I disorder. Major depressive disorder and other anxiety disorders were most common comorbid disorders. Lifetime alcohol use disorders also showed marked frequency. Interestingly, the remission rates of alcohol use disorders were notable. The panic symptoms appeared to persist for years. Panic disorder was associated with low education and relatively low probability of working full time. Conclusions. Also in primary care panic disorder is comorbid, chronic, and disabling. It is important to recognize the comorbid disorders. High remission rates of comorbid alcohol use disorders encourage active treatment of patients also suffering from these disorders.
机译：目的。尽管70-80％的恐慌症患者使用初级保健获得心理健康服务，但是在这种情况下，相对较少的研究检查了惊恐症患者。这项研究的目的是检查与初级保健中恐慌症相关的终生和当前合并症精神病，疾病的持续时间和严重程度以及与之相关的社会人口统计学因素。设计。对患者进行恐慌症筛查。使用针对DSM-IV轴I和II的《结构化临床访谈》确定恐慌症和合并症。设置。埃斯波市的八个初级保健机构均设有保健中心。主题。 18至65岁之间的芬兰语。主要观察指标。合并症，精神疾病，疾病的持续时间和严重程度以及社会人口统计学因素。结果。确定了49名恐慌症患者和44名目前没有精神病诊断的患者的样本。 98％的恐慌症患者患有至少一种合并性终生DSM-IV轴心病。重度抑郁症和其他焦虑症是最常见的合并症。终生饮酒障碍也显示出明显的频率。有趣的是，饮酒障碍的缓解率很明显。恐慌症状似乎持续多年。恐慌症与低学历和全职工作的可能性相对较低有关。结论。同样在初级保健中，恐慌症是合并症，慢性病和残疾。认识到合并症很重要。合并使用酒精障碍的高缓解率鼓励积极治疗也患有这些障碍的患者。

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