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首页> 外文期刊>Journal of Fluorescence >Study on the Synthesis and Spectra of a Novel Kind of Carbozole Benzothiazole Indole Styryl Cyanine Dye with a Carbazole Bridged Chain
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Study on the Synthesis and Spectra of a Novel Kind of Carbozole Benzothiazole Indole Styryl Cyanine Dye with a Carbazole Bridged Chain

机译：新型咔唑桥连式咔唑苯并噻唑吲哚苯乙烯基花菁染料的合成与光谱研究

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摘要

Based on the frequently-used cyanine dye probe thiazole orange (TO) and Cy3, a novel kind of styryl cyanine dye was designed and synthesized. Carbazole was inserted into the structures of two cyanine dyes, TO and Cy3, to act as a bridge to link the benzothiazole and indole. This modification resulted in a novel kind of carbozole benzothiazole indole cyanine dye with a carbazole-bridged chain. The dyes were characterized by HNMR and MS. The spectra of the novel dyes were also studied and the results showed that the fluorescence wavelength of novel carbazole benzothiazole indole cyanine dye shifted red, the Stokes shift and Fluorescence quantum yields increased and the fluorescence intensity was enhanced compared to that of TO. These results indicated that the novel dye could be used as an excellent fluorescent probe in biological labeling.
机译：基于常用的花青染料探针噻唑橙（TO）和Cy3，设计合成了一种新型的苯乙烯基花青染料。将咔唑插入到两种花青染料TO和Cy3的结构中，以充当连接苯并噻唑和吲哚的桥。这种修饰产生了一种新型的带有咔唑桥连的咔唑苯并噻唑吲哚花菁染料。染料通过HNMR和MS表征。对新型染料的光谱进行了研究，结果表明，与TO相比，新型咔唑苯并噻唑吲哚花菁染料的荧光波长发生红移，斯托克斯频移和荧光量子产率提高，荧光强度增强。这些结果表明，该新型染料可作为生物标记中的优良荧光探针。

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