...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of genetics >Benefits of being biased!
【24h】

Benefits of being biased!

机译：有偏见的好处！

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The genetic code is degenerate: most amino acids are coded by multiple codons. However, it is known that certain codons for a given amino acid are preferred over other synonymous codons. Theoretical studies have predicted and experiments have shown that this kind of a bias can lead to higher efficiency of translation, presumably accompanied by benefits in terms of the Darwinian fitness of the organism. However, population genetics models based on gene sequence data predict that, at least for certain organisms like the fruit fly, Drosophila melanogaster, the fitness effects might be too small to be observed. Two recent studies (Carlini and Stephan 2003; Carlini 2004) show that even in such systems, under certain conditions, it is possible to empirically demonstrate the effects of codon bias at the phenotypic level, and the corresponding effect on at least one major component of the fitness of the organism.
机译：遗传密码简并性：大多数氨基酸由多个密码子编码。然而，已知给定氨基酸的某些密码子优于其他同义密码子。理论研究已经进行了预测，实验表明这种偏见可以提高翻译效率，并可能带来达尔文式适应性方面的好处。但是，基于基因序列数据的种群遗传模型预测，至少对于某些生物，例如果蝇，果蝇（Drosophila melanogaster），适应性影响可能太小而无法观察到。最近的两项研究（Carlini和Stephan 2003; Carlini 2004）表明，即使在这样的系统中，在一定条件下，也有可能在表型水平上凭经验证明密码子偏倚的影响，以及对至少一种主要成分的相应影响。有机体的适应性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号