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首页> 外文期刊>Journal of glaucoma >Comparison of Neuroretinal Rim Area Measurements Made by the Heidelberg Retina Tomograph i and the Heidelberg Retina Tomograph II
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Comparison of Neuroretinal Rim Area Measurements Made by the Heidelberg Retina Tomograph i and the Heidelberg Retina Tomograph II

机译：海德堡视网膜断层扫描仪i和海德堡视网膜断层扫描仪II进行的神经视网膜边缘区域测量的比较

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PURPOSE:: To investigate the agreement between neuroretinal rim area (RA) measurements using the Heidelberg Retina Tomograph I (HRT Classic) and Heidelberg Retina Tomograph II (HRT II). To compare apparent RA changes in follow-up series of HRT II topographies when using either an HRT Classic or HRT II mean topography as baseline. DESIGN:: Cross-sectional study and "no-change," short time series study. PARTICIPANTS:: Forty-three ocular hypertensive and 31 primary open angle glaucoma subjects. METHODS:: Five HRT Classic and 5 HRT II examinations were acquired from 1 eye of each subject, across 2 visits within 6 weeks. For the cross-sectional study, follow-up RA measurements from HRT Classic and HRT II were compared, using the same HRT Classic mean topography as the baseline. The linear rates of RA change were compared in 2 short time series with either an HRT Classic or an HRT II mean topography as baseline, and 4 follow-up HRT II mean topographies. Intervals between topographies were arbitrarily set at 1 year for meaningful comparisons of rates. Rates of RA change over time were calculated by linear regression. Separate analyses were performed using 3 available reference planes (RP). MAIN OUTCOME MEASURES:: Global and sectoral RA measurements in HRT Classic and HRT II mean topographies; linear rates of RA change. RESULTS:: HRT Classic minus HRT II mean differences (95% limits of agreement) were 0.09 (-0.17, 0.35) mm, 0.09 (-0.13, 0.32) mm, and 0.11 (-0.24, 0.46) mm for the Moorfields, 320 μm, and standard RPs, respectively (P<0.001 for all RPs, Wilcoxon rank sum test). In the time series, the mean differences (95% limits of agreement) of RA rates of change (HRT Classic baseline minus HRT II baseline) were -0.01 (-0.06, 0.03) mm/y, -0.01 (-0.06, 0.04) mm/y, and -0.0 (-0.09, 0.05) mm/y using the Moorfields, 320 μm, and standard RPs, respectively. CONCLUSION:: Although HRT software is backward-compatible, follow-up RA measurements made in the same eye using HRT Classic and HRT II devices display statistically and clinically meaningful systematic differences when HRT Classic topographies are used as a baseline.
机译：目的：：调查使用海德堡视网膜断层扫描仪I（HRT经典版）和海德堡视网膜断层扫描仪II（HRT II）进行神经视网膜边缘区域（RA）测量之间的一致性。为了比较在使用HRT Classic或HRT II平均地形作为基线的后续系列HRT II地形中的明显RA变化。设计：：横断面研究和“不变”短时间序列研究。参与者：43眼高血压和31例原发性开角型青光眼受试者。方法：在6周内，从每位受试者的1只眼中进行了5次HRT Classic和5次HRT II检查。对于横断面研究，使用相同的HRT Classic平均地形作为基线，比较了HRT Classic和HRT II的后续RA测量值。在2个短时间序列中，以HRT Classic或HRT II平均地形为基线，比较了4个随访的HRT II平均地形，比较了RA变化的线性率。地形之间的间隔任意设置为1年，以便对比率进行有意义的比较。 RA随时间的变化率通过线性回归计算。使用3个可用的参考平面（RP）进行了单独的分析。主要观察指标：HRT Classic和HRT II平均地形的全球和部门RA测量; RA的线性变化率。结果:: HRT Classic减去HRT II平均差（95％的协议限制）分别为0.09（-0.17，0.35）mm，0.09（-0.13，0.32）mm和Mo1fields的0.11（-0.24，0.46）mm，320分别为μm和标准RP（对于所有RP，P <0.001，Wilcoxon秩和检验）。在时间序列中，RA变化率（HRT经典基线减去HRT II基线）的平均差异（95％一致限制）为-0.01（-0.06，0.03）mm / y，-0.01（-0.06，0.04） mm / y和分别使用Moorfields，320μm和标准RP的-0.0（-0.09，0.05）mm / y。结论：尽管HRT软件是向后兼容的，但是当以HRT Classic地形为基准时，使用HRT Classic和HRT II设备在同一只眼中进行的后续RA测量显示出统计学上和临床上有意义的系统差异。

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