首页> 外文期刊>Journal of gastroenterology and hepatology >Marshall and Warren Lecture 2009: Peptic Ulcer Bleeding: An expedition of 20 years from 1989-2009.
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Marshall and Warren Lecture 2009: Peptic Ulcer Bleeding: An expedition of 20 years from 1989-2009.

机译:马歇尔和沃伦2009年讲座:消化性溃疡出血:从1989年至2009年为期20年的探险。

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摘要

Peptic ulcer bleeding is one of the most common medical emergencies leading to substantial mortality and morbidity. The last two decades has witnessed some important advances in the management of this condition, and some of these are results from clinical trials conducted in the Asia Pacific region. The optimal use of combined endoscopic hemostasis and the use of pharmacologic control of acid secretion in the stomach have significantly improved clinical outcome. The role of surgery has been redefined. Treatment of Helicobacter pylori infection and prophylactic treatment in non-steroidal anti-inflammatory drug and anti-platelet users have made progress in preventing recurrence of peptic ulcer and bleeding. Instead of merely focusing on safety in the gastrointestinal tract, striking a balance between risk and benefit of continuing anti-platelet agents should be a top agenda.
机译:消化性溃疡出血是导致大量死亡和发病的最常见的医学紧急情况之一。在过去的二十年中,该病的管理取得了一些重要进展,其中一些是在亚太地区进行的临床试验的结果。组合内镜止血的最佳使用和胃酸分泌的药理控制的使用显着改善了临床结局。手术的作用已被重新定义。非甾体类抗炎药和抗血小板药物使用者对幽门螺杆菌感染的治疗和预防性治疗在预防消化性溃疡和出血复发方面取得了进展。不仅要着眼于胃肠道的安全性,而且要在继续使用抗血小板药的风险与收益之间取得平衡,应该是头等大事。

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