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首页> 外文期刊>Journal of hepato-biliary-pancreatic surgery >Aggressive surgery for liver metastases from gastrointestinal stromal tumors.
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Aggressive surgery for liver metastases from gastrointestinal stromal tumors.

机译：积极进行胃肠道间质瘤肝转移手术。

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Background/Purpose. The utility of hepatectomy for patients with metastatic liver tumors from gastrointestinal stromal tumors (GISTs) was evaluated in the present study. Methods. Between 1989 and 2001, ten patients with liver metastases from GIST (four men and six women; age, 34-77 years) underwent hepatectomy at our hospital. All patients underwent complete resection of the primary tumor and hepatectomy with or without microwave coagulation therapy (MCT) for all detectable hepatic tumors. Results. The median survival time after hepatectomy was 39 months (range, 1 to 96 months). There was one postoperative death. One patient is still alive with relapse of hepatic tumors, and the remaining eight patients died of disease (liver in six, peritoneum in one, and bone in one). Relapse of hepatic tumors occurred in seven patients. The disease-free rate after hepatectomy was 22% at 2 years and 11% at 5 years. The survival times of the four patients who received hepatic arterial chemoembolization for recurrent hepatic metastases were 7 months (still alive), 17, 23, and 28 months (average, 19 months). Conclusions. Our data suggest that aggressive surgery (hepatectomy and MCT) for all detectable hepatic tumors and hepatic arterial chemoembolization for recurrent hepatic metastases improve survival.
机译：背景/目的。在本研究中评估了肝切除术在胃肠道间质瘤（GIST）转移性肝肿瘤患者中的应用。方法。在1989年至2001年之间，我们医院对10例来自GIST的肝转移患者（四男六女;年龄34-77岁）进行了肝切除术。所有患者均对所有可检测到的肝肿瘤进行了原发性肿瘤的完全切除和肝切除术，有或没有微波凝固疗法（MCT）。结果。肝切除术后中位生存时间为39个月（1到96个月）。术后有1例死亡。一名患者仍存活着，并伴有肝肿瘤的复发，其余八名患者死于疾病（肝六例，腹膜一例，骨一例）。 7例患者发生肝肿瘤复发。肝切除术后2年的无病率和5年的11％。四例因复发性肝转移接受肝动脉化学栓塞术的患者的生存时间分别为7个月（仍活着），17、23和28个月（平均19个月）。结论。我们的数据表明，对所有可检测到的肝肿瘤进行积极的手术（肝切除术和MCT），对复发性肝转移进行肝动脉化学栓塞治疗可以提高生存率。

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