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首页> 外文期刊>Journal of hepato-biliary-pancreatic surgery >Undifferentiated carcinoma of the common bile duct: case report and review of the literature.
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Undifferentiated carcinoma of the common bile duct: case report and review of the literature.

机译:胆总管未分化癌:病例报告及文献复习。

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摘要

A 78-year-old Japanese man with undifferentiated carcinoma of the common bile duct is presented. Upon gross examination, the common bile duct was found to be obstructed by a nodule measuring 10 x 10 mm. Microscopically, the nodule was ill-defined and composed of atypical spindle-shaped and pleomorphic tumor cells. The spindle-shaped cells proliferated in a whirled or interlacing pattern simulating a sarcoma, and the pleomorphic tumor cells had abundant eosinophilic cytoplasm and bizarre nuclei. Histochemically, a few tumor cells contained mucosubstances stained with the alcian blue (AB) method in their cytoplasm. Immunohistochemically, the tumor cells were diffusely positive for CAM5.2 and AE1/AE3. The histological diagnosis was undifferentiated carcinoma (spindle cell carcinoma) of the common bile duct. Other than our patient, only four other cases of undifferentiated carcinoma in the extrahepatic bile duct have been reported in the literature.
机译:介绍了一名78岁的日本男子,未发生胆总管癌。粗略检查后,发现胆总管被大小为10 x 10 mm的结节阻塞。在显微镜下,结节定义不清,由非典型纺锤形和多形肿瘤细胞组成。纺锤形细胞以旋转或交错的模式增殖,模拟肉瘤,多形肿瘤细胞具有丰富的嗜酸性细胞质和奇异的细胞核。组织化学上,一些肿瘤细胞的细胞质中含有用阿尔辛蓝(AB)法染色的粘膜物质。免疫组织化学分析,肿瘤细胞对CAM5.2和AE1 / AE3呈弥漫阳性。组织学诊断为胆总管未分化癌(纺锤状细胞癌)。除我们的患者外,文献中仅报道了肝外胆管中其他四例未分化癌。

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