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The effect of weekly iron supplementation on anaemia and on iron deficiency among female tea pluckers in Bangladesh.

机译:孟加拉国每周补铁对女性采茶者贫血和缺铁的影响。

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AIM: To investigate the effect of weekly iron supplementation on anaemia and iron deficiency among adult, female tea pluckers. METHOD: A randomized double-blind intervention trial was conducted in a tea estate in Bangladesh where a total of 280 women received either weekly iron supplementation (200 mg ferrous fumarate and 200 mg folic acid) for 24 weeks or a matching placebo. Capillary blood samples were drawn at baseline and post-trial to determine haemoglobin, haematocrit and ferritin concentration. Mean corpuscular haemoglobin concentration (MCHC) was calculated using the haemoglobin and haematocrit values. RESULTS: The mean haemoglobin concentration in the supplemented group increased by 5.52 g L-1 over the study period, on average, while ferritin values decreased by 0.33 microgram L-1. The control group showed a decrease in both mean haemoglobin (-0.24 g L-1) and ferritin (-5.32 micrograms L-1). Those individuals in the supplemented group with the lowest pretrial haemoglobin and ferritin values experienced the greatest improvements post-trial, whereas nonanaemic individuals showed a decrease in both haemoglobin and ferritin concentrations. A total of 62.2% of women in the supplemented group reported feeling better and more energetic compared to 51.1% in the placebo group; 14.4% of the supplemented group and 22.7% of the control group complained about side-effects. CONCLUSION: Weekly iron supplementation was logistically simpler and cheaper than daily supplementation but would have to be continued on a longer term basis in order to combat both anaemia and iron deficiency.
机译:目的:探讨每周补充铁对成年雌性采茶者贫血和缺铁的影响。方法:在孟加拉的一家茶馆中进行了一项随机双盲干预试验,该试验中共有280名妇女接受了每周铁补充剂(200 mg富马酸亚铁和200 mg叶酸)的补充,为期24周。在基线和试验后抽取毛细管血样,以确定血红蛋白,血细胞比容和铁蛋白浓度。使用血红蛋白和血细胞比容值计算平均红细胞血红蛋白浓度(MCHC)。结果:在研究期间,补充组的平均血红蛋白浓度平均增加5.52 g L-1,而铁蛋白值减少0.33微克L-1。对照组的平均血红蛋白(-0.24 g L-1)和铁蛋白(-5.32微克L-1)均降低。补充组中那些具有最低的审前血红蛋白和铁蛋白值的人在审判后经历了最大的改善,而非贫血的人则显示血红蛋白和铁蛋白的浓度均下降。与安慰剂组的51.1%相比,补充组中的总女性中有62.2%的人感觉更好,更有活力。补充组的14.4%和对照组的22.7%抱怨有副作用。结论:从逻辑上讲,每周补铁比每天补铁在逻辑上更简单,更便宜,但为了对抗贫血和铁缺乏症,必须长期服用。

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