A flexible pentacene thin film transistors as disposable DNA hybridization sensor

Jung-Min Kim; Sandeep Kumar Jha; Dong-Hoon Lee

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A flexible pentacene thin film transistors as disposable DNA hybridization sensor

机译：柔性并五苯薄膜晶体管作为一次性DNA杂交传感器

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We fabricated a disposable DNA hybridization sensor using pentacene thin film transistors (TFTs) on flexible substrate. The analytes, 100-mer ss-DNA (poly A and poly T) or 100 bp ds-DNA were immobilized directly on the surface of the pentacene layer, thereby producing a dramatic change in the electrical properties of the devices. The electrical characteristics of devices were studied as a function of DNA immobilization conditions, DNA concentrations and between ss- and ds-DNA. Based on these results, we propose a disposable label-free sensor for DNA hybridization through direct measurement of electrical properties by the immobilization of DNA on flexible pentacene TFTs.

机译：我们在柔性基板上使用并五苯薄膜晶体管（TFT）制造了一次性DNA杂交传感器。将分析物100-mer ss-DNA（poly A和poly T）或100 bp ds-DNA直接固定在并五苯层的表面上，从而在器件的电性能上产生了巨大变化。研究了装置的电学特性与DNA固定条件，DNA浓度以及ss-和ds-DNA之间的关系。基于这些结果，我们提出了一种通过将DNA固定在柔性并五苯TFT上直接测量电性能来进行DNA杂交的一次性无标记传感器。

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《Journal of industrial and engineering chemistry》 |2012年第5期|共5页
作者
Jung-Min Kim; Sandeep Kumar Jha; Dong-Hoon Lee;
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正文语种 eng
中图分类化学工业;
关键词
Hybridization sensor; Pentacene thin film transistor; Disposable sensor; Label-free;

机译：杂交传感器;并五苯薄膜晶体管;一次性传感器;无标签;

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专利

1. A flexible pentacene thin film transistors as disposable DNA hybridization sensor [J] . Jung-Min Kim, Sandeep Kumar Jha, Dong-Hoon Lee Journal of industrial and engineering chemistry . 2012,第5期

机译：柔性并五苯薄膜晶体管作为一次性DNA杂交传感器
2. DNA hybridization detection with organic thin film transistors: Toward fast and disposable DNA microarray chips [J] . Zhang QT, Subramanian V Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices . 2007,第12期

机译：使用有机薄膜晶体管进行DNA杂交检测：面向快速和一次性DNA微阵列芯片
3. Key Issues With Printed Flexible Thin Film Transistors and Their Application in Disposable RF Sensors [J] . Noh Jinsoo, Jung Minhoon, Jung Younsu, Proceedings of the IEEE . 2015,第4期

机译：印刷柔性薄膜晶体管的关键问题及其在一次性射频传感器中的应用
4. Flexible pentacene thin film transistors as DNA hybridization sensor [C] . Kim Jung-Min, Jha Sandeep Kumar, Chand Rohit, Proceedings of the 2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems . 2011

机译：柔性并五苯薄膜晶体管作为DNA杂交传感器
5. Tips pentacene crystal alignment for improving performance of solution processed organic thin film transistors. [D] . He, Zhengran. 2014

机译：并五苯晶体取向的技巧，以提高溶液处理的有机薄膜晶体管的性能。
6. Stability Study of Flexible 613-Bis(triisopropylsilylethynyl)pentacene Thin-Film Transistors with a Cross-Linked Poly(4-vinylphenol)/Yttrium Oxide Nanocomposite Gate Insulator [O] . Jin-Hyuk Kwon, Xue Zhang, Shang Hao Piao, 2016

机译：带有交联聚（4-乙烯基苯酚）/氧化钇纳米复合栅极绝缘子的柔性613-双（三异丙基甲硅烷基乙炔基）并五苯薄膜晶体管的稳定性研究
7. Stability Study of Flexible 6,13-Bis(triisopropylsilylethynyl)pentacene Thin-Film Transistors with a Cross-Linked Poly(4-vinylphenol)/Yttrium Oxide Nanocomposite Gate Insulator [O] . Jin-Hyuk Kwon, Xue Zhang, Shang Hao Piao, 2016

机译：具有交联聚（4-乙烯基苯酚）/氧化钇纳米复合栅绝缘子的柔性6,13-双（三异丙基甲硅烷基乙炔基）并五苯薄膜晶体管的稳定性研究
8. Pentacene Organic Thin-Film Transistors on Flexible Paper and Glass Substrates. [R] . A. J. Steckl A. T. Zocco H. You J. A. Hagen 2014

机译：柔性纸和玻璃基板上的并五苯有机薄膜晶体管。

A flexible pentacene thin film transistors as disposable DNA hybridization sensor

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