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首页> 外文期刊>Journal of industrial and engineering chemistry >pH-dependent release of alginate beads coated with polylysine
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pH-dependent release of alginate beads coated with polylysine

机译：pH依赖性释放包被多赖氨酸的藻酸盐微珠

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摘要

Alginate beads were coated with basic proteinoid, polylysine (PL), by taking advantage of an electrostatic interaction in order to obtain a controlled release in response to change in pH. When the amount of PL adsorbed on the surface of alginate beads was 1.77 g PL/1.0 g alginate, the loading efficiency of FITC-dextran was about 82%. In the range of pH 5.0-9.0, the degrees of release in 240 min were relatively high, around 70%, and there was no significant effect of pH on the degree of release. At pH 3.5 and pH 4.0, the releases were markedly suppressed and the degrees of release were about 33% and 50%, respectively. At lower pHs, the amino groups of PL will be more protonated, so the coating layer would become compact due to a strong electrostatic interaction. In fact, the degrees of swelling of alginate beads at pH 3.5 and pH 4.0 were lower than the values at the other pHs.
机译：通过利用静电相互作用将碱性蛋白样多聚赖氨酸（PL）覆盖在藻酸盐微珠上，以获得响应pH值变化的控制释放。当藻酸盐珠粒表面吸附的PL的量为1.77g PL / 1.0g藻酸盐时，FITC-葡聚糖的负载效率为约82％。在pH 5.0-9.0范围内，240分钟内的释放度相对较高，约为70％，并且pH值对释放度没有显着影响。在pH 3.5和pH 4.0下，释放明显受到抑制，释放程度分别约为33％和50％。在较低的pH值下，PL的氨基会更质子化，因此涂层会由于强的静电相互作用而变得致密。实际上，在pH 3.5和pH 4.0时藻酸盐珠的溶胀度低于其他pH值。

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