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首页> 外文期刊>Journal of laparoendoscopic and advanced surgical techniques, Part A >Therapeutic efficacy of endoscopic retrograde cholangiopancreatography among pregnant women with severe acute biliary pancreatitis.
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Therapeutic efficacy of endoscopic retrograde cholangiopancreatography among pregnant women with severe acute biliary pancreatitis.

机译：内镜逆行胰胆管造影对重症急性胆源性胰腺炎孕妇的治疗效果。

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To explore the feasibility of endoscopic retrograde cholangiopancreatography (ERCP) in pregnant women with severe acute biliary pancreatitis.In total, 24 pregnant patients with severe acute biliary pancreatitis were enrolled in our study between January 2003 and January 2008. Emergency ERCP and endoscopic nasobiliary drainage (ENBD) without fluoroscopy were performed successfully in all 24 patients within 12-72 hours of admission. Once stabilized, 15 patients in late pregnancy underwent a second ERCP with fluoroscopy to remove common bile duct (CBD) stones after pregnancy termination. Nine patients in early or mid-pregnancy continued gestating and underwent endoscopic retrograde biliary drainage (ERBD) with a second ERCP without fluoroscopy, and their stents and CBD stones were removed during a third ERCP with fluoroscopy 1 week after parturition.Among the mothers, all 24 patients were cured, and none of them died. The CBD stones in all 24 patients were completely removed with a two-step ERCP, and no serious post-ERCP complications occurred, although 2 patients had mild hemorrhage in the final ERCP to remove CBD stones. No recurrent pancreatitis or cholangitis occurred in patients who underwent ERBD. Among the infants, all survived without developmental problems or abnormality. Twenty infants were born at term; four infants were born prematurely at 35-37 weeks of gestation without developmental problems or complications.Emergency ERCP and ENBD without fluoroscopy in pregnant women with severe acute biliary pancreatitis are feasible and safe for both mothers and infants. It is also appropriate to remove CBD stones with two-step ERCP in pregnant women according to the stage of pregnancy.
机译：为了探讨内镜逆行胰胆管造影术（ERCP）在重症急性胆源性胰腺炎孕妇中的可行性。我们在2003年1月至2008年1月之间共纳入了24例重症急性胆源性胰腺炎孕妇。急诊ERCP和内镜鼻胆管引流术（入院后12-72小时内，所有24例患者均成功进行了无荧光检查的ENBD检查。一旦稳定下来，妊娠末期的15例患者将接受第二次ERCP透视检查，以在终止妊娠后去除胆总管（CBD）结石。九名怀孕初期或中期孕妇继续妊娠，并在未进行透视的情况下接受了第二次ERCP的内镜逆行胆管引流术（ERBD），并且在分娩后1周进行了透视的第三次ERCP术中移除了支架和CBD结石。 24例患者治愈，无一死亡。尽管有2名患者在最后的ERCP中有轻度出血，但采用两步ERCP彻底清除了所有24例患者的CBD结石，并且未发生严重的ERCP术后并发症。接受ERBD的患者未发生复发性胰腺炎或胆管炎。在婴儿中，所有婴儿均存活，没有发育问题或异常。足月出生的婴儿有20名。四名婴儿在妊娠35-37周时早产，没有发育问题或并发症。对于患有严重急性胆源性胰腺炎的孕妇，紧急的ERCP和ENBD无需透视检查对母亲和婴儿都是可行且安全的。根据怀孕阶段，也可以通过两步ERCP清除孕妇的CBD结石。

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