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Faculty involvement in translational research and interdisciplinary collaboration at a US academic medical center.

机译:在美国学术医学中心,教师参与转化研究和跨学科合作。

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BACKGROUND: Forty-six academic health centers have been awarded Clinical and Translational Science Awards by the National Institutes of Health to enhance health by advancing translational research. OBJECTIVE: As a recipient of a Clinical and Translational Science Award, we aimed to determine the prevalence of translational and interdisciplinary collaboration at our institution. DESIGN, SETTING, AND PARTICIPANTS: We surveyed all full-time faculty and postdoctoral fellows (n = 3870) in the Johns Hopkins Schools of Medicine, Public Health, Nursing and Engineering, in late 2008. MAIN OUTCOME MEASURES: Outcomes included (1) the proportion of investigators involved in early (T1), late (T2), and reverse translational (RT) research; (2) barriers to translational research; (3) attitudes about translational research; (4) involvement in interdisciplinary collaboration; and (5) barriers to collaboration. RESULTS: With 1800 respondents, the response rate was 55% for faculty and 40% for postdoctoral fellows. Of the 1314 investigators with more than 30% of their time committed to research, 69% reported conducting 1 or more types of translational research (T1 = 79%, T2 = 36%, RT = 36%). Attitudes about translational research revealed both concern and uncertainty. Fifty-four percent of respondents described translational research as having complex regulatory requirements; 42% felt that an individual's contributions suffer from underrecognition, 39% described it as high risk, and 35% consider funding less secure for translational researchers. Collaboration across school and types of research was common. Forty-seven percent of basic scientists collaborated with a clinical investigator in the last year, and 56% of clinical investigators collaborated with a basic scientist. CONCLUSIONS: Overall, investigators who did translational research reported a greater number of collaborators than those who did not.
机译:背景:46个学术健康中心已被美国国立卫生研究院授予临床和转化科学奖,以通过推进转化研究来增强健康。目的:作为临床和转化科学奖的获得者,我们旨在确定我们机构中翻译和跨学科合作的普遍性。设计,地点和参加者:我们于2008年末对约翰霍普金斯医学院,公共卫生,护理和工程学院的所有专职教师和博士后进行了调查(n = 3870)。主要观察指标:包括结果(1)参与早期(T1),晚期(T2)和反向翻译(RT)研究的研究者比例; (2)转化研究的障碍; (三)对翻译研究的态度; (4)参与跨学科合作; (5)合作的障碍。结果:1800名受访者中,教师的回应率为55%,博士后的回应率为40%。在1314名研究人员中,有30%以上的时间致力于研究,其中69%的研究人员报告进行了一种或多种翻译研究(T1 = 79%,T2 = 36%,RT = 36%)。对转化研究的态度揭示了关注和不确定性。 54%的受访者称翻译研究具有复杂的法规要求; 42%的人认为个人的贡献受到忽视,39%的人认为这是高风险的,35%的人认为资金不足以保证翻译研究人员的安全。整个学校和研究类型之间的合作很普遍。去年,有47%的基础科学家与临床研究人员合作,而56%的临床研究人员与基础科学家合作。结论:总体而言,从事翻译研究的研究人员报告的合作者数量多于未进行合作研究的研究人员。

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