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首页> 外文期刊>Journal of Internal Medicine >Favourable trends in the incidence and outcome of myocardial infarction in nondiabetic, but not in diabetic, subjects: findings from the MONICA myocardial infarction registry in northern Sweden in 1989-2000.
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Favourable trends in the incidence and outcome of myocardial infarction in nondiabetic, but not in diabetic, subjects: findings from the MONICA myocardial infarction registry in northern Sweden in 1989-2000.

机译:非糖尿病患者(而非糖尿病患者)心肌梗塞的发生率和预后的有利趋势:1989-2000年瑞典北部莫尼卡心肌梗塞注册中心的发现。

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摘要

Background: The aim of this study was to compare time trends in incidence, case fatality and mortality due to myocardial infarction (MI) in patients with or without diabetes. Methods: This study was based on the Northern Sweden MONICA Project MI registry with a target population of about 200 000 inhabitants in the age group 35-64 years in the two northernmost counties of Sweden. During 1989-2000, 6254 patients who had had an MI according to MONICA criteria were included in this study: 4569 patients had a first MI and 1685 had a recurrent MI. Sixteen per cent of the men and 20% of the women had had diabetes mellitus diagnosed prior the MI. Results: Over the 12-year period, there was a declining trend in incidence and case fatality in first MI. Also, the event rates (first ever and recurrent MI) declined in men without diabetes. In women without diabetes favourable time trends were seen in first ever MI, recurrent MI and in case fatality. There were no favourable time trends for any of these outcomes in patients with diabetes. Conclusion: In nondiabetic subjects below the age of 65, the incidence of, and case-fatality in, MI declined. This led to a decreased mortality over the 12-year period. These favourable trends over time were not observed in diabetic subjects.
机译:背景:本研究的目的是比较患有或不患有糖尿病的患者因心肌梗塞(MI)引起的发病率,病死率和死亡率的时间趋势。方法:本研究基于瑞典北部MONICA Project MI注册表,目标群体是瑞典最北端两个县的35-64岁年龄段的约200 000居民。在1989-2000年期间,该研究纳入了6254名根据MONICA标准患有MI的患者:4569例患有首次MI的患者和1685例复发了MI。 16%的男性和20%的女性在MI前被诊断出患有糖尿病。结果:在过去的12年中,首发MI的发病率和病死率呈下降趋势。同样,没有糖尿病的男性的事件发生率(首次发生和复发性心肌梗死)下降。在没有糖尿病的女性中,有史以来首次心梗,复发性心肌梗塞和死亡病例的时间趋势良好。糖尿病患者中任何一种预后都没有有利的时间趋势。结论:在65岁以下的非糖尿病受试者中,MI的发生率和病死率均下降。这导致在12年内死亡率降低。在糖尿病受试者中未观察到这些随时间的有利趋势。

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