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首页> 外文期刊>Journal of Lipid Research >Effects of palm oil and transesterified palm oil on chylomicron and VLDL triacylglycerol structures and postprandial lipid response.
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Effects of palm oil and transesterified palm oil on chylomicron and VLDL triacylglycerol structures and postprandial lipid response.

机译：棕榈油和酯交换的棕榈油对乳糜微粒和VLDL三酰基甘油结构以及餐后脂质反应的影响。

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摘要

The effects of positional distribution of triacylglycerol (TAG) fatty acids to TAG structures in chylomicrons and VLDL, and to postprandial lipemia, were studied in 10 healthy premenopausal women using a 6-h oral fat load test and a randomized, double-blind cross-over design. Molecular level information of TAG regioisomerism was obtained with a tandem mass spectrometric method. The positional distribution of fatty acids in chylomicron TAGs was similar to the respective dietary fat; 79% of the analyzed regioisomers in palm oil and 84% of the analyzed regioisomers in transesterified oil were found in chylomicron TAGs 3 h after the oral fat loads. VLDL TAGs were equal after the two fat loads in all but one regioisomer. Similarities in the fatty acid compositions of chylomicron TAGs suggest that palmitic acid was absorbed equally from both test fats. The proportion of palmitoleic acid in the chylomicrons was increased. Fat with palmitic acid predominantly in the sn-1 and sn-3 positions caused a larger incremental area of total TAGs in plasma and reduced plasma insulin values at the beginning of the postprandial response (0-90 min) compared with fat with palmitic acid randomly distributed. The relationship between TAG molecular structures in dietary fats and in lipoproteins provides new means for understanding the effects of fatty acid positional distribution on human lipid metabolism.
机译：使用6小时口服脂肪负荷测试和随机双盲交叉研究，研究了10名健康的绝经前女性中三酰基甘油（TAG）脂肪酸的位置分布对乳糜微粒和VLDL中的TAG结构以及餐后血脂的影响。过度设计。 TAG区域异构的分子水平信息是通过串联质谱法获得的。乳糜微粒TAGs中脂肪酸的位置分布与各自的饮食脂肪相似。口服脂肪负荷3小时后，在乳糜微粒TAG中发现了棕榈油中79％的分析区域异构体和酯交换油中84％的分析区域异构体。 VLDL TAGs在除一个区域异构体以外的所有区域都具有两个脂肪负载后相等。乳糜微粒TAG的脂肪酸组成相似，表明棕榈酸从两种测试脂肪中均被吸收。乳糜微粒中棕榈油酸的比例增加。与随机含棕榈酸的脂肪相比，含棕榈酸的脂肪主要位于sn-1和sn-3位置，导致餐后反应开始时（0-90分钟）血浆中总TAG的增加面积更大，血浆胰岛素值降低。分散式。膳食脂肪和脂蛋白中TAG分子结构之间的关系为理解脂肪酸位置分布对人体脂质代谢的影响提供了新的手段。

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