...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Lipid Research >Thematic review series: Lipid droplet synthesis and metabolism: From yeast to man: Lipid droplets as fat storage organelles in Caenorhabditis elegans
【24h】

Thematic review series: Lipid droplet synthesis and metabolism: From yeast to man: Lipid droplets as fat storage organelles in Caenorhabditis elegans

机译：专题回顾系列：脂滴的合成与代谢：从酵母到人：脂滴在秀丽隐杆线虫中作为脂肪储存细胞器

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Lipid droplets are evolutionarily conserved organelles where cellular fat storage and mobilization are exquisitely regulated. Recent studies have defined lipid droplets in C. elegans and explored how they are regulated by genetic and dietary factors. C. elegans offers unique opportunities to visualize lipid droplets at single-cell resolution in live animals. The development of novel microscopy techniques and protein markers for lipid droplets will accelerate studies on how nutritional states and subcellular organization are linked in vivo. Together with powerful tools for genetic and biochemical analysis of metabolic pathways, alteration in lipid droplet abundance, size, and distribution in C. elegans can be readily connected to whole-animal energy homeostasis, behavior, and life span. Therefore, further studies on lipid droplets in C. elegans promise to yield valuable insights that complement our knowledge gained from yeast, Drosophila, and mammalian systems on cellular and organismal fat storage.
机译：脂质小滴是进化保守的细胞器，细胞脂肪的储存和移动受到精确调节。最近的研究已经定义了秀丽隐杆线虫中的脂质滴，并探索了它们如何受到遗传和饮食因素的调节。秀丽隐杆线虫提供了独特的机会以活细胞中的单细胞分辨率可视化脂质滴。新型显微镜技术和脂滴蛋白标记物的发展将加速关于体内营养状态和亚细胞组织如何联系的研究。连同用于代谢途径的遗传和生化分析的强大工具，秀丽隐杆线虫中脂滴丰度，大小和分布的变化，可以很容易地与整个动物的能量稳态，行为和寿命联系起来。因此，对秀丽隐杆线虫中的脂质滴的进一步研究有望产生有价值的见解，以补充我们从酵母，果蝇和哺乳动物系统中获得的有关细胞和生物脂肪储存的知识。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号