...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Korean medical science >Endobronchial ultrasound-guided transbronchial needle biopsy for diagnosis of mediastinal lymphadenopathy in patients with extrathoracic malignancy.
【24h】

Endobronchial ultrasound-guided transbronchial needle biopsy for diagnosis of mediastinal lymphadenopathy in patients with extrathoracic malignancy.

机译：支气管内超声引导下经支气管穿刺活检诊断胸外恶性肿瘤纵隔淋巴结病。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Mediastinal lymphadenopathy associated with extrathoracic malignancy or a metastasis of unknown origin (MUO) requires pathological verification. Surgical exploration or endoscopic ultrasound-guided fine needle aspiration is limited to application. We investigated the effectiveness of endobronchial ultrasound-guided transbronchial needle biopsy (EBUS-TBNA) for evaluating mediastinal lymphadenopathy in patients with an extrathoracic malignancy. We retrospectively analyzed data from 59 patients who underwent EBUS-TBNA with a core biopsy because of a suspected mediastinal metastasis between September 2008 and August 2010. All patients had previously been diagnosed with an extrathoracic malignancy (n = 39, 66.1%) or a suspected MUO without a thoracic lesion (n = 20, 33.9%). A total of 88 lymph nodes was analyzed. EBUS-TBNA findings indicated malignancies in 34 patients (57.6%). The EBUS-TBNA sensitivity and specificity for the detection of mediastinal malignancy in patients with a previous extrathoracic malignancy were 96.3% and 100%, respectively. For MUO patients without a thoracic lesion, the sensitivity and specificity were 61.5% and 100%, respectively. The overall sensitivity and specificity were 81.0% and 100%, respectively (P = 0.053). EBUS-TBNA is a safe and effective modality for evaluating mediastinal lymphadenopathy in patients with a previous extrathoracic malignancy or a MUO without a thoracic lesion. The application of this diagnostic tool is likely to have significant clinical implications.
机译：与胸外恶性肿瘤或未知来源转移（MUO）相关的纵隔淋巴结肿大需要病理学验证。手术探查或内窥镜超声引导的细针抽吸术仅限于应用。我们调查了支气管内超声引导下经支气管穿刺活检（EBUS-TBNA）在评估胸外恶性肿瘤纵隔淋巴结病中的有效性。我们回顾性分析了2008年9月至2010年8月间因疑似纵隔转移而行EBUS-TBNA活检的59例患者的数据。所有患者先前均被诊断出胸外恶性肿瘤（n = 39，66.1％）或疑似无胸腔病变的MUO（n = 20，33.9％）。总共分析了88个淋巴结。 EBUS-TBNA的发现表明34例患者发生了恶性肿瘤（57.6％）。 EBUS-TBNA对先前有胸外恶性肿瘤的纵隔恶性肿瘤检测的敏感性和特异性分别为96.3％和100％。对于没有胸腔病变的MUO患者，敏感性和特异性分别为61.5％和100％。总体敏感性和特异性分别为81.0％和100％（P = 0.053）。 EBUS-TBNA是评估先前有胸外恶性肿瘤或无胸腔病变的MUO患者的纵隔淋巴结肿大的一种安全有效的方法。此诊断工具的应用可能会对临床产生重大影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号