• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of mass spectrometry: JMS >Comparison of triple quadrupole mass spectrometry and Orbitrap high-resolution mass spectrometry in ultrahigh performance liquid chromatography for the determination of veterinary drugs in sewage: benefits and drawbacks
【24h】

Comparison of triple quadrupole mass spectrometry and Orbitrap high-resolution mass spectrometry in ultrahigh performance liquid chromatography for the determination of veterinary drugs in sewage: benefits and drawbacks

机译：超高效液相色谱法测定污水中兽药的三重四极杆质谱与Orbitrap高分辨率质谱的比较：优点和缺点

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This paper presents a comparison of triple quadrupole tandem mass spectrometry (MS/MS) and Orbitrap high-resolution mass spectrometry (HRMS) combined to ultrahigh performance liquid chromatography for the determination of glucocorticoids and polyether ionophores in sewage, in order to show the major benefits and drawbacks for each mass spectrometry analyser. Overall, HRMS measurements have enhanced performance in terms of confirmatory capabilities than MS/MS measurements. Moreover, similar limits of quantification, limits of detection, linear range and repeatability for glucocorticoids with both the MS/MS and HRMS methods were compared, but in the case of polyether ionophores, slightly better limits of detection and limits of quantification were obtained with the HRMS method because of the high sensitivity obtained when diagnostic ions are used for quantification instead of selected reaction monitoring transitions for these compounds. The two methods have been applied to the analysis of several influent and effluent sewage samples from sewage treatment plants located in the Tarragona region (Catalonia, Spain), showing an excellent correlation between the two methods.
机译：本文比较了三重四极杆串联质谱（MS / MS）和Orbitrap高分辨率质谱（HRMS）与超高效液相色谱法测定污水中的糖皮质激素和聚醚离子载体的比较，以显示主要优点每个质谱分析仪的缺点和缺点。总体而言，与MS / MS测量相比，HRMS测量在确认能力方面具有增强的性能。此外，使用MS / MS和HRMS方法对糖皮质激素的定量限，检出限，线性范围和可重复性进行了比较，但对于聚醚离子载体，使用HPLC获得了更好的检出限和定量限。 HRMS方法，因为当使用诊断离子进行定量而不是针对这些化合物的选定反应监测转换时，获得了很高的灵敏度。这两种方法已用于分析塔拉戈纳地区（西班牙加泰罗尼亚）的污水处理厂的几种进水和出水污水样品，显示出这两种方法之间的良好关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号