...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association >Combined endoscopy, aspiration, and biopsy analysis for identifying infectious colitis in patients with ileocecal ulcers.
【24h】

Combined endoscopy, aspiration, and biopsy analysis for identifying infectious colitis in patients with ileocecal ulcers.

机译：内窥镜，抽吸和活检相结合的分析可用于确定回盲肠溃疡患者的感染性结肠炎。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The ileocecal area is commonly involved in infection and inflammatory colonic diseases, but differential diagnosis can be difficult. We identified definitive endoscopic findings and a sample collection method for diagnosing infectious colitis.In a retrospective study, we analyzed data on 128 patients with ileocecal ulcer who underwent colonoscopy from 2007-2011 at the National Center for Global Health and Medicine in Tokyo, Japan. We collected information on location, size, number, and distinctive endoscopic findings and estimated diagnostic odds ratios (ORs). The sensitivities of microscopy, culture, polymerase chain reaction, and histologic methods in identifying patients with infection were compared with those of standard stool, endoscopic aspirated intestinal fluid, or biopsy analyses.Of the 128 patients, 100 had infections, and 28 had Crohn's disease, Beh?et's disease, or other inflammatory diseases. Predictive endoscopic findings were as follows: for amebiasis of the cecum (OR, 17.8), with exudates (OR, 13.9) and round-shaped ulcer (OR, 5.77); for tuberculosis (TB) with transverse-shaped ulcer (OR, 175), scar (OR, 34.6), linear-shaped ulcer (OR, 23.9), or ≥10 mm (OR, 14.0); for cytomegalovirus with round-shaped ulcer (OR, 4.09); and for Campylobacter with cecal valve lesion (OR, 58.3) or ≥10 mm (OR, 10.4). The sensitivity of endoscopic sample collection was significantly higher than that of standard stool sample collection for the diagnosis of amebiasis, TB, non-TB mycobacteria, and other bacteria (P < .05). The methods that detected infection with the highest levels of sensitivity were biopsy with histology for amebiasis, biopsy with culture for TB, biopsy with polymerase chain reaction for cytomegalovirus, and aspiration of intestinal fluid with culture for Campylobacter.Combining results from endoscopic analysis with appropriate sample collection and pathogen detection methods enables infectious colitis to be differentiated from other noninfectious colonic diseases.
机译：回盲区通常参与感染和结肠炎性疾病，但鉴别诊断可能很困难。我们确定了明确的内窥镜检查结果和诊断感染性结肠炎的样本收集方法。在一项回顾性研究中，我们分析了2007年至2011年在日本东京国立全球健康与医学中心接受结肠镜检查的128例回盲肠溃疡患者的数据。我们收集了有关位置，大小，数量和独特的内窥镜检查结果以及估计的诊断比值比（OR）的信息。将显微镜，培养，聚合酶链反应和组织学方法识别感染患者的敏感性与标准粪便，内窥镜抽吸肠液或活检分析的敏感性进行了比较.128例患者中有100例感染，其中28例患有克罗恩氏病，行为病或其他炎症性疾病。预测的内窥镜检查结果如下：盲肠的氨虫病（OR，17.8），有渗出液（OR，13.9）和圆形溃疡（OR，5.77）;用于患有横形溃疡（OR，175），疤痕（OR，34.6），线形溃疡（OR，23.9）或≥10mm（OR，14.0）的结核病（TB）;用于圆形溃疡的巨细胞病毒（OR，4.09）;对于盲肠病变的弯曲杆菌（OR，58.3）或≥10mm（OR，10.4）。内窥镜样本采集对阿米巴病，结核病，非结核分枝杆菌和其他细菌的诊断敏感性显着高于标准粪便样本采集（P <.05）。敏感性最高的检测方法是组织学的阿米巴病活检，结核菌的活检，巨细胞病毒的聚合酶链反应活检，弯曲菌培养的肠液吸取，结合内镜分析的结果和适当的样本收集和病原体检测方法可使传染性结肠炎与其他非传染性结肠疾病区分开来。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号